TY - JOUR
T1 - Genome-wide SNP analysis of Siamese cobra (Naja kaouthia) reveals the molecular basis of transitions between Z and W sex chromosomes and supports the presence of an ancestral super-sex chromosome in amniotes
AU - Laopichienpong, Nararat
AU - Kraichak, Ekaphan
AU - Singchat, Worapong
AU - Sillapaprayoon, Siwapech
AU - Muangmai, Narongrit
AU - Suntrarachun, Sunutcha
AU - Baicharoen, Sudarath
AU - Peyachoknagul, Surin
AU - Chanhome, Lawan
AU - Ezaz, Tariq
AU - Srikulnath, Kornsorn
N1 - Funding Information:
This study was financially supported by grants from the Center for Advanced Studies in Tropical Natural Resources, National Research University-Kasetsart University (CASTNAR, NRU-KU, Thailand) (no. 6/2558 and 9/2559) awarded to KS, the Capacity Building of KU Students on Internationalization Program (KUCSI) awarded to NL and KS, Thailand Research Fund (TRF) (no. RSA6180075 and PHD60I0014) awarded to KS and WS, and Science Achievement Scholarship of Thailand (SAST) (no. 5917400296) from the Office of the Higher Education Commission, Thailand awarded to NL.
Funding Information:
This study was financially supported by grants from the Center for Advanced Studies in Tropical Natural Resources, National Research University-Kasetsart University (CASTNAR, NRU-KU, Thailand) (no. 6/2558 and 9/2559 ) awarded to KS, the Capacity Building of KU Students on Internationalization Program (KUCSI) awarded to NL and KS, Thailand Research Fund (TRF) (no. RSA6180075 and PHD60I0014 ) awarded to KS and WS, and Science Achievement Scholarship of Thailand (SAST) (no. 5917400296 ) from the Office of the Higher Education Commission , Thailand awarded to NL.
Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2021/1
Y1 - 2021/1
N2 - Elucidation of the process of sex chromosome differentiation is necessary to understand the dynamics of evolutionary mechanisms in organisms. The W sex chromosome of the Siamese cobra (Naja kaouthia) contains a large number of repeats and shares amniote sex chromosomal linkages. Diversity Arrays Technology provides an effective approach to identify sex-specific loci that are epoch-making, to understand the dynamics of molecular transitions between the Z and W sex chromosomes in a snake lineage. From a total of 543 sex-specific loci, 90 showed partial homology with sex chromosomes of several amniotes and 89 loci were homologous to transposable elements. Two loci were confirmed as W-specific nucleotides after PCR amplification. These loci might result from a sex chromosome differentiation process and involve putative sex-determination regions in the Siamese cobra. Sex-specific loci shared linkage homologies among amniote sex chromosomes, supporting an ancestral super-sex chromosome.
AB - Elucidation of the process of sex chromosome differentiation is necessary to understand the dynamics of evolutionary mechanisms in organisms. The W sex chromosome of the Siamese cobra (Naja kaouthia) contains a large number of repeats and shares amniote sex chromosomal linkages. Diversity Arrays Technology provides an effective approach to identify sex-specific loci that are epoch-making, to understand the dynamics of molecular transitions between the Z and W sex chromosomes in a snake lineage. From a total of 543 sex-specific loci, 90 showed partial homology with sex chromosomes of several amniotes and 89 loci were homologous to transposable elements. Two loci were confirmed as W-specific nucleotides after PCR amplification. These loci might result from a sex chromosome differentiation process and involve putative sex-determination regions in the Siamese cobra. Sex-specific loci shared linkage homologies among amniote sex chromosomes, supporting an ancestral super-sex chromosome.
KW - DArTseq™
KW - Sex chromosome differentiation
KW - Siamese cobra
KW - Snake
KW - SNP
UR - http://www.scopus.com/inward/record.url?scp=85092101908&partnerID=8YFLogxK
U2 - 10.1016/j.ygeno.2020.09.058
DO - 10.1016/j.ygeno.2020.09.058
M3 - Article
AN - SCOPUS:85092101908
SN - 0888-7543
VL - 113
SP - 624
EP - 636
JO - Genomics
JF - Genomics
IS - 1P2
ER -