Aging causes deterioration in kidney function leading to chronic kidney disease. Chronic kidney disease has been associated with oxidative stress, increased circulating levels of inflammatory markers, phosphate retention with medial vascular calcification, increased parathyroid hormone concentrations causing valvular calcification and dysfunction, anemia, and left ventricular hypertrophy, all of which can increase cardiovascular risk. Among lifestyle factors, diet plays an important role in the prevention of renal failure. Although, there is no specific dietary pattern for preventing renal failure, excessive intake of protein, sodium, potassium and alcohol have shown to be related with the progression of renal failure even among elderly individuals; while the well-balanced Mediterranean diet has been related with preserved renal function. Fish and polyunsaturated fatty acids (PUFA) consumption has been favorably related to the prognosis of kidney function, mainly due to the anti-inflammatory properties of PUFA, as well as to its negative correlation with blood pressure levels.
|Title of host publication||Molecular Basis of Nutrition and Aging|
|Subtitle of host publication||A Volume in the Molecular Nutrition Series|
|Editors||Marco Malavolta, Eugenio Mocchegiani|
|Place of Publication||Netherlands|
|Number of pages||9|
|Publication status||Published - 28 Apr 2016|