Hypertrophic cardiomyopathy and ultra-endurance running - Two incompatible entities?

Mathew G. Wilson, Navin Chandra, Michael Papadakis, Rory O'Hanlon, Sanjay K. Prasad, Sanjay Sharma

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)
24 Downloads (Pure)


Regular and prolonged exercise is associated with increased left ventricular wall thickness that can overlap with hypertrophic cardiomyopathy (HCM). Differentiating physiological from pathological hypertrophy has important implications, since HCM is the commonest cause of exercise-related sudden cardiac death in young individuals. Most deaths have been reported in intermittent 'start-stop' sports such as football (soccer) and basketball. The theory is that individuals with HCM are unable to augment stroke volume sufficiently to meet the demands of endurance sports and are accordingly 'selected-out' of participation in such events. We report the case of an ultra-endurance athlete with 25 years of > 50 km competitive running experience, with genetically confirmed HCM; thereby demonstrating that these can be two compatible entities.

Original languageEnglish
Article number77
Pages (from-to)1-9
Number of pages9
JournalJournal of Cardiovascular Magnetic Resonance
Issue number1
Publication statusPublished - 2011
Externally publishedYes


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