Abstract
Relaxin immunoreactivity has been found in samples of human follicular fluid collected from artificially stimulated pre-ovulatory follicles. The crude extract caused a reduction in the height of the contractions in a rat uterine strip bioassay. The reactive material eluted from Sephadex G50 in two major peaks. The first contained ̃ 60% of the immunoreactivity and had an elution position corresponding to that of porcine relaxin, indicating a mol. wt of ̃ 6000 daltons. The second peak was of a lower mol. wt, but its exact size and significance are unknown. A possible role for relaxin in the process of follicular rupture is suggested.
| Original language | English |
|---|---|
| Pages (from-to) | 515-517 |
| Number of pages | 3 |
| Journal | Human Reproduction |
| Volume | 1 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1 Dec 1986 |
| Externally published | Yes |
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Cite this
Wathes, D. C., Wardle, P. G., Rees, J. M., Mitchell, J. D., Mclaughlin, E. A., Hull, M. G. R., & Porter, D. G. (1986). Identification of relaxin immunoreactivity in human follicular fluid. Human Reproduction, 1(8), 515-517. https://doi.org/10.1093/oxfordjournals.humrep.a136465