Abstract
Relaxin immunoreactivity has been found in samples of human follicular fluid collected from artificially stimulated pre-ovulatory follicles. The crude extract caused a reduction in the height of the contractions in a rat uterine strip bioassay. The reactive material eluted from Sephadex G50 in two major peaks. The first contained ̃ 60% of the immunoreactivity and had an elution position corresponding to that of porcine relaxin, indicating a mol. wt of ̃ 6000 daltons. The second peak was of a lower mol. wt, but its exact size and significance are unknown. A possible role for relaxin in the process of follicular rupture is suggested.
Original language | English |
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Pages (from-to) | 515-517 |
Number of pages | 3 |
Journal | Human Reproduction |
Volume | 1 |
Issue number | 8 |
DOIs | |
Publication status | Published - 1 Dec 1986 |
Externally published | Yes |