TY - JOUR
T1 - IMI - Myopia Control Reports Overview and Introduction
AU - Wolffsohn, James S
AU - Flitcroft, Daniel Ian
AU - Gifford, Kate L
AU - Jong, Monica
AU - Jones, Lyndon
AU - Klaver, Caroline C W
AU - Logan, Nicola S
AU - Naidoo, Kovin
AU - Resnikoff, Serge
AU - Sankaridurg, Padmaja
AU - Smith, Earl L
AU - Troilo, David
AU - Wildsoet, Christine F
N1 - Funding Information:
The authors thank David Sullivan, the chief executive of the Tear Film and Ocular Surface Society, for sharing his expertise in putting together global consensuses. An individual who contributed significantly to this paper wishes to remain anonymous and declined authorship or acknowledgment. Supported by the International Myopia Institute. The publication costs of the International Myopia Institute reports were supported by donations from the Brien Holden Vision Institute, Carl Zeiss Vision, CooperVision, Essilor, Alcon, and Vision Impact Institute.
Funding Information:
The authors thank David Sullivan, the chief executive of the Tear Film and Ocular Surface Society, for sharing his expertise in putting together global consensuses. An individual who contributed significantly to this paper wishes to remain anonymous and declined authorship or acknowledgment. Supported by the International Myopia Institute. The publication costs of the International Myopia Institute reports were supported by donations from the Brien Holden Vision Institute, Carl Zeiss Vision, CooperVision, Essilor, Alcon, and Vision Impact Institute. Disclosure: J.S. Wolffsohn, Alcon (F), Allergan (F), Aston EyeTech (F, I), Atiya Vision (C), Bausch & Lomb (F), BetterVision Ltd. (F), British Contact Lens Association (C), CooperVision (F, C), Eaglet Eye (F), European Union (F), Eyebag (F), EMPharma (F), EyeDocs (F), Gelflex (F), Innovate UK (F), Johnson & Johnson Vision Care (F, C, R), Lenstec (F), Medmont (F), Optimec (F), Rayner (F), RB (C), Santen (C, R), Shire (C), Tearlab (F), Théa (F), University of Houston (C), Visioncare Research (F, C), P; D.I. Flitcroft, None; K.L. Gifford, Myopia Profile Pty Ltd. (I), CooperVision (C), Menicon (C), Alcon (R), CooperVision (R), Menicon (R), Vision-eering Technologies (R); M. Jong, None; L. Jones, Alcon (F, C, R), Allergan (F), Contamac (F), CooperVision (F, C, R), Essilor (F), GL Chemtec (F), Inflamax Research (F), J&J Vision (F, C, R), Menicon (F), Nature’s Way (F), Novartis (F, C, R), Ophtecs (C, R), Safilens (F), Santen (F), Shire (F), SightGlass (F), TearLab (F), TearScience and Visioneering (F); C.C.W. Klaver, Topcon (F), Thea Pharma (C); N.S. Logan, CooperVision, Visioncare Research (F); K. Naidoo, None; S. Resnikoff, Brien Holden Vision Institute (C); P. Sankaridurg, Brien Holden Vision Institute (E), P; E.L. Smith
Publisher Copyright:
© 2019 The Authors.
PY - 2019/2/28
Y1 - 2019/2/28
N2 - With the growing prevalence of myopia, already at epidemic levels in some countries, there is an urgent need for new management approaches. However, with the increasing number of research publications on the topic of myopia control, there is also a clear necessity for agreement and guidance on key issues, including on how myopia should be defined and how interventions, validated by well-conducted clinical trials, should be appropriately and ethically applied. The International Myopia Institute (IMI) reports the critical review and synthesis of the research evidence to date, from animal models, genetics, clinical studies, and randomized controlled trials, by more than 85 multidisciplinary experts in the field, as the basis for the recommendations contained therein. As background to the need for myopia control, the risk factors for myopia onset and progression are reviewed. The seven generated reports are summarized: (1) Defining and Classifying Myopia, (2) Experimental Models of Emmetropization and Myopia, (3) Myopia Genetics, (4) Interventions for Myopia Onset and Progression, (5) Clinical Myopia Control Trials and Instrumentation, (6) Industry Guidelines and Ethical Considerations for Myopia Control, and (7) Clinical Myopia Management Guidelines.
AB - With the growing prevalence of myopia, already at epidemic levels in some countries, there is an urgent need for new management approaches. However, with the increasing number of research publications on the topic of myopia control, there is also a clear necessity for agreement and guidance on key issues, including on how myopia should be defined and how interventions, validated by well-conducted clinical trials, should be appropriately and ethically applied. The International Myopia Institute (IMI) reports the critical review and synthesis of the research evidence to date, from animal models, genetics, clinical studies, and randomized controlled trials, by more than 85 multidisciplinary experts in the field, as the basis for the recommendations contained therein. As background to the need for myopia control, the risk factors for myopia onset and progression are reviewed. The seven generated reports are summarized: (1) Defining and Classifying Myopia, (2) Experimental Models of Emmetropization and Myopia, (3) Myopia Genetics, (4) Interventions for Myopia Onset and Progression, (5) Clinical Myopia Control Trials and Instrumentation, (6) Industry Guidelines and Ethical Considerations for Myopia Control, and (7) Clinical Myopia Management Guidelines.
KW - Animals
KW - Disease Progression
KW - Humans
KW - Internationality
KW - Myopia/classification
KW - Prevalence
KW - Risk Factors
KW - Vision Disorders/prevention & control
U2 - 10.1167/iovs.18-25980
DO - 10.1167/iovs.18-25980
M3 - Review article
C2 - 30817825
SN - 0146-0404
VL - 60
SP - 1
EP - 19
JO - Investigative ophthalmology & visual science
JF - Investigative ophthalmology & visual science
IS - 3
ER -