Improving Body Composition May Reduce the Immune and Inflammatory Responses of Firefighters Working in the Heat

Anthony Walker, Heather E.Wright Beatty, Sara Zanetti, Ben Rattray

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Objective: We hypothesized that different body composition and fitness of firefighters would affect immune and inflammatory activity after working in the heat. Methods: Forty-two firefighters worked in the heat (100 ± 5 °C). Changes in leukocytes, platelets, tumor necrosis factor (TNF-α), and C-reactive protein (CRP) were analyzed based on body composition (DXA) and aerobic fitness (VO 2max). Results: Higher baseline leukocytes were observed for high body fat (P = 0.002) and low lean mass (P = 0.023) resulting in the highest peak values. Additionally, significantly lower values for TNF-α were observed with high lean mass at all time points. Platelets were unaffected by fitness or body composition. Furthermore, body mass index (BMI) and VO 2max played no role. Conclusions: Minimizing body fat and increasing lean mass may reduce immune and inflammatory activity of firefighters in the heat.

    Original languageEnglish
    Pages (from-to)377-383
    Number of pages7
    JournalJournal of Occupational and Environmental Medicine
    Volume59
    Issue number4
    DOIs
    Publication statusPublished - 1 Apr 2017

    Fingerprint

    Firefighters
    Body Composition
    Hot Temperature
    Adipose Tissue
    Leukocytes
    Blood Platelets
    Lymphotoxin-beta
    C-Reactive Protein
    Body Mass Index
    Tumor Necrosis Factor-alpha

    Cite this

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    title = "Improving Body Composition May Reduce the Immune and Inflammatory Responses of Firefighters Working in the Heat",
    abstract = "Objective: We hypothesized that different body composition and fitness of firefighters would affect immune and inflammatory activity after working in the heat. Methods: Forty-two firefighters worked in the heat (100 ± 5 °C). Changes in leukocytes, platelets, tumor necrosis factor (TNF-α), and C-reactive protein (CRP) were analyzed based on body composition (DXA) and aerobic fitness (VO 2max). Results: Higher baseline leukocytes were observed for high body fat (P = 0.002) and low lean mass (P = 0.023) resulting in the highest peak values. Additionally, significantly lower values for TNF-α were observed with high lean mass at all time points. Platelets were unaffected by fitness or body composition. Furthermore, body mass index (BMI) and VO 2max played no role. Conclusions: Minimizing body fat and increasing lean mass may reduce immune and inflammatory activity of firefighters in the heat.",
    author = "Anthony Walker and Beatty, {Heather E.Wright} and Sara Zanetti and Ben Rattray",
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    Improving Body Composition May Reduce the Immune and Inflammatory Responses of Firefighters Working in the Heat. / Walker, Anthony; Beatty, Heather E.Wright; Zanetti, Sara; Rattray, Ben.

    In: Journal of Occupational and Environmental Medicine, Vol. 59, No. 4, 01.04.2017, p. 377-383.

    Research output: Contribution to journalArticle

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    AU - Beatty, Heather E.Wright

    AU - Zanetti, Sara

    AU - Rattray, Ben

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