Incidence des accidents coronariens sévères chez des patients coronariens stentés pratiquants un sport en competition

Translated title of the contribution: Incidence of major adverse cardiac events in men wishing to continue competitive sport following percutaneous coronary intervention

Jean Michel Guy, Mathew Wilson, Frédéric Schnell, Laurent Chevalier, Jean Claude Verdier, Sonia Corone, Stéphane Doutreleau, Gaelle Kervio, François Carré

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: The new North American guidelines for participation in competitive sport in patients with coronary artery disease (CAD) are less restrictive than previous guidelines. Aim: To evaluate the incidence of major adverse cardiac events (MACE) in men with CAD who practise intensive physical activity after a stenting procedure. MACE included in-stent restenosis (SR), stent thrombosis (ST), new coronary stenosis (NCS), myocardial infarction, heart failure, cardiac arrest or cardiac death. Methods: Asymptomatic men with CAD and a coronary stent who practised regular (>4 h/week) sport were included in this retrospective multicentre observational study. All patients presented with left ventricular ejection fraction ≥ 50%, no residual stenosis, and no inducible ischaemia or arrhythmias. Three groups were compared: those undertaking moderate leisure-time sport (MLS), intensive leisure-time sport (ILS) or competitive sport (CS). During follow-up, all patients had a yearly routine cardiology evaluation. Results: A total of 108 men with CAD (57.3 ± 9.1 years) were included: 29 MLS, 58 ILS, and 21 CS. During follow-up (57.6 ± 46.0 months) the incidence of MACE was 15.7% (SR = 5, SR + NCS = 4, ST = 4, NCS = 4) and occurred during physical exertion in 59% of patients. ST was more frequent in the CS (n = 3) than in the MLS (n = 1) or ILS (n = 0) groups, especially in patients with bare-metal stents. Conclusions: The incidence of MACE was 15.7%, and only ST was significantly more frequent in CS patients than in MLS or ILS patients. Our data support the new US guidelines for exercise eligibility in men with CAD.

Original languageFrench
Pages (from-to)226-233
Number of pages8
JournalArchives of Cardiovascular Diseases
Volume112
Issue number4
DOIs
Publication statusPublished - Apr 2019

Fingerprint

Percutaneous Coronary Intervention
Sports
Leisure Activities
Stents
Incidence
Coronary Artery Disease
Coronary Stenosis
Thrombosis
Guidelines
Exercise
Physical Exertion
Heart Arrest
Cardiology
Stroke Volume
Multicenter Studies
Observational Studies
Cardiac Arrhythmias
Pathologic Constriction
Ischemia
Heart Failure

Cite this

Guy, Jean Michel ; Wilson, Mathew ; Schnell, Frédéric ; Chevalier, Laurent ; Verdier, Jean Claude ; Corone, Sonia ; Doutreleau, Stéphane ; Kervio, Gaelle ; Carré, François. / Incidence des accidents coronariens sévères chez des patients coronariens stentés pratiquants un sport en competition. In: Archives of Cardiovascular Diseases. 2019 ; Vol. 112, No. 4. pp. 226-233.
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title = "Incidence des accidents coronariens s{\'e}v{\`e}res chez des patients coronariens stent{\'e}s pratiquants un sport en competition",
abstract = "Background: The new North American guidelines for participation in competitive sport in patients with coronary artery disease (CAD) are less restrictive than previous guidelines. Aim: To evaluate the incidence of major adverse cardiac events (MACE) in men with CAD who practise intensive physical activity after a stenting procedure. MACE included in-stent restenosis (SR), stent thrombosis (ST), new coronary stenosis (NCS), myocardial infarction, heart failure, cardiac arrest or cardiac death. Methods: Asymptomatic men with CAD and a coronary stent who practised regular (>4 h/week) sport were included in this retrospective multicentre observational study. All patients presented with left ventricular ejection fraction ≥ 50{\%}, no residual stenosis, and no inducible ischaemia or arrhythmias. Three groups were compared: those undertaking moderate leisure-time sport (MLS), intensive leisure-time sport (ILS) or competitive sport (CS). During follow-up, all patients had a yearly routine cardiology evaluation. Results: A total of 108 men with CAD (57.3 ± 9.1 years) were included: 29 MLS, 58 ILS, and 21 CS. During follow-up (57.6 ± 46.0 months) the incidence of MACE was 15.7{\%} (SR = 5, SR + NCS = 4, ST = 4, NCS = 4) and occurred during physical exertion in 59{\%} of patients. ST was more frequent in the CS (n = 3) than in the MLS (n = 1) or ILS (n = 0) groups, especially in patients with bare-metal stents. Conclusions: The incidence of MACE was 15.7{\%}, and only ST was significantly more frequent in CS patients than in MLS or ILS patients. Our data support the new US guidelines for exercise eligibility in men with CAD.",
keywords = "Coronary heart disease, Sport, Stent restenosis, Stent thrombosis",
author = "Guy, {Jean Michel} and Mathew Wilson and Fr{\'e}d{\'e}ric Schnell and Laurent Chevalier and Verdier, {Jean Claude} and Sonia Corone and St{\'e}phane Doutreleau and Gaelle Kervio and Fran{\cc}ois Carr{\'e}",
year = "2019",
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Guy, JM, Wilson, M, Schnell, F, Chevalier, L, Verdier, JC, Corone, S, Doutreleau, S, Kervio, G & Carré, F 2019, 'Incidence des accidents coronariens sévères chez des patients coronariens stentés pratiquants un sport en competition', Archives of Cardiovascular Diseases, vol. 112, no. 4, pp. 226-233. https://doi.org/10.1016/j.acvd.2018.11.008

Incidence des accidents coronariens sévères chez des patients coronariens stentés pratiquants un sport en competition. / Guy, Jean Michel; Wilson, Mathew; Schnell, Frédéric; Chevalier, Laurent; Verdier, Jean Claude; Corone, Sonia; Doutreleau, Stéphane; Kervio, Gaelle; Carré, François.

In: Archives of Cardiovascular Diseases, Vol. 112, No. 4, 04.2019, p. 226-233.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Incidence des accidents coronariens sévères chez des patients coronariens stentés pratiquants un sport en competition

AU - Guy, Jean Michel

AU - Wilson, Mathew

AU - Schnell, Frédéric

AU - Chevalier, Laurent

AU - Verdier, Jean Claude

AU - Corone, Sonia

AU - Doutreleau, Stéphane

AU - Kervio, Gaelle

AU - Carré, François

PY - 2019/4

Y1 - 2019/4

N2 - Background: The new North American guidelines for participation in competitive sport in patients with coronary artery disease (CAD) are less restrictive than previous guidelines. Aim: To evaluate the incidence of major adverse cardiac events (MACE) in men with CAD who practise intensive physical activity after a stenting procedure. MACE included in-stent restenosis (SR), stent thrombosis (ST), new coronary stenosis (NCS), myocardial infarction, heart failure, cardiac arrest or cardiac death. Methods: Asymptomatic men with CAD and a coronary stent who practised regular (>4 h/week) sport were included in this retrospective multicentre observational study. All patients presented with left ventricular ejection fraction ≥ 50%, no residual stenosis, and no inducible ischaemia or arrhythmias. Three groups were compared: those undertaking moderate leisure-time sport (MLS), intensive leisure-time sport (ILS) or competitive sport (CS). During follow-up, all patients had a yearly routine cardiology evaluation. Results: A total of 108 men with CAD (57.3 ± 9.1 years) were included: 29 MLS, 58 ILS, and 21 CS. During follow-up (57.6 ± 46.0 months) the incidence of MACE was 15.7% (SR = 5, SR + NCS = 4, ST = 4, NCS = 4) and occurred during physical exertion in 59% of patients. ST was more frequent in the CS (n = 3) than in the MLS (n = 1) or ILS (n = 0) groups, especially in patients with bare-metal stents. Conclusions: The incidence of MACE was 15.7%, and only ST was significantly more frequent in CS patients than in MLS or ILS patients. Our data support the new US guidelines for exercise eligibility in men with CAD.

AB - Background: The new North American guidelines for participation in competitive sport in patients with coronary artery disease (CAD) are less restrictive than previous guidelines. Aim: To evaluate the incidence of major adverse cardiac events (MACE) in men with CAD who practise intensive physical activity after a stenting procedure. MACE included in-stent restenosis (SR), stent thrombosis (ST), new coronary stenosis (NCS), myocardial infarction, heart failure, cardiac arrest or cardiac death. Methods: Asymptomatic men with CAD and a coronary stent who practised regular (>4 h/week) sport were included in this retrospective multicentre observational study. All patients presented with left ventricular ejection fraction ≥ 50%, no residual stenosis, and no inducible ischaemia or arrhythmias. Three groups were compared: those undertaking moderate leisure-time sport (MLS), intensive leisure-time sport (ILS) or competitive sport (CS). During follow-up, all patients had a yearly routine cardiology evaluation. Results: A total of 108 men with CAD (57.3 ± 9.1 years) were included: 29 MLS, 58 ILS, and 21 CS. During follow-up (57.6 ± 46.0 months) the incidence of MACE was 15.7% (SR = 5, SR + NCS = 4, ST = 4, NCS = 4) and occurred during physical exertion in 59% of patients. ST was more frequent in the CS (n = 3) than in the MLS (n = 1) or ILS (n = 0) groups, especially in patients with bare-metal stents. Conclusions: The incidence of MACE was 15.7%, and only ST was significantly more frequent in CS patients than in MLS or ILS patients. Our data support the new US guidelines for exercise eligibility in men with CAD.

KW - Coronary heart disease

KW - Sport

KW - Stent restenosis

KW - Stent thrombosis

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U2 - 10.1016/j.acvd.2018.11.008

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