Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise

Kevin THOMPSON, Louise Turner, Jonathon Prichard, Fiona Dodd, David Kennedy, Crystal Haskell-Ramsay, Jamie Blackwell, Andrew Jones

    Research output: Contribution to journalArticle

    44 Citations (Scopus)

    Abstract

    Dietary inorganic nitrate supplementation causes physiological effects which may enhance exercise tolerance. However it is not known whether nitrate might alter cognitive function during exercise. In a double-blind, cross-over study, sixteen subjects ingested either nitrate-rich beetroot juice or a placebo and completed a continuous cycle exercise test involving 20min stages at 50% and 70% V˙O2peak and a final stage at 90% V˙O2peak until volitional exhaustion. Cognitive tasks were completed before, during and after exercise. In the dietary nitrate condition: plasma [nitrite] increased (p<0.01), systolic blood pressure decreased (p<0.05) and there was a trend for a reduced oxygen uptake at 50% V˙O2peak. Tissue oxygenation improved across exercise intensities and exercise tolerance was greater at 90% V˙O2peak (p<0.05). Rating of perceived exertion, energy levels and cognitive performance were similar between conditions with mental fatigue being evident from 70% V˙O2peak onwards (p<0.05). Dietary nitrate supplementation enhanced short-term endurance exercise performance with concomitant mental fatigue but did not improve cognitive performance post-fatigue.

    Original languageEnglish
    Pages (from-to)11-20
    Number of pages10
    JournalRespiratory Physiology and Neurobiology
    Volume193
    Issue number1
    DOIs
    Publication statusPublished - 1 Mar 2014

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    Dietary Supplements
    Nitrates
    Mental Fatigue
    Exercise Tolerance
    Blood Pressure
    Nitrites
    Exercise Test
    Cross-Over Studies
    Cognition
    Fatigue
    Placebos
    Oxygen

    Cite this

    THOMPSON, Kevin ; Turner, Louise ; Prichard, Jonathon ; Dodd, Fiona ; Kennedy, David ; Haskell-Ramsay, Crystal ; Blackwell, Jamie ; Jones, Andrew. / Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise. In: Respiratory Physiology and Neurobiology. 2014 ; Vol. 193, No. 1. pp. 11-20.
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    abstract = "Dietary inorganic nitrate supplementation causes physiological effects which may enhance exercise tolerance. However it is not known whether nitrate might alter cognitive function during exercise. In a double-blind, cross-over study, sixteen subjects ingested either nitrate-rich beetroot juice or a placebo and completed a continuous cycle exercise test involving 20min stages at 50{\%} and 70{\%} V˙O2peak and a final stage at 90{\%} V˙O2peak until volitional exhaustion. Cognitive tasks were completed before, during and after exercise. In the dietary nitrate condition: plasma [nitrite] increased (p<0.01), systolic blood pressure decreased (p<0.05) and there was a trend for a reduced oxygen uptake at 50{\%} V˙O2peak. Tissue oxygenation improved across exercise intensities and exercise tolerance was greater at 90{\%} V˙O2peak (p<0.05). Rating of perceived exertion, energy levels and cognitive performance were similar between conditions with mental fatigue being evident from 70{\%} V˙O2peak onwards (p<0.05). Dietary nitrate supplementation enhanced short-term endurance exercise performance with concomitant mental fatigue but did not improve cognitive performance post-fatigue.",
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    Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise. / THOMPSON, Kevin; Turner, Louise; Prichard, Jonathon; Dodd, Fiona; Kennedy, David; Haskell-Ramsay, Crystal; Blackwell, Jamie; Jones, Andrew.

    In: Respiratory Physiology and Neurobiology, Vol. 193, No. 1, 01.03.2014, p. 11-20.

    Research output: Contribution to journalArticle

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    AU - THOMPSON, Kevin

    AU - Turner, Louise

    AU - Prichard, Jonathon

    AU - Dodd, Fiona

    AU - Kennedy, David

    AU - Haskell-Ramsay, Crystal

    AU - Blackwell, Jamie

    AU - Jones, Andrew

    N1 - Copyright © 2014 Elsevier B.V. All rights reserved.

    PY - 2014/3/1

    Y1 - 2014/3/1

    N2 - Dietary inorganic nitrate supplementation causes physiological effects which may enhance exercise tolerance. However it is not known whether nitrate might alter cognitive function during exercise. In a double-blind, cross-over study, sixteen subjects ingested either nitrate-rich beetroot juice or a placebo and completed a continuous cycle exercise test involving 20min stages at 50% and 70% V˙O2peak and a final stage at 90% V˙O2peak until volitional exhaustion. Cognitive tasks were completed before, during and after exercise. In the dietary nitrate condition: plasma [nitrite] increased (p<0.01), systolic blood pressure decreased (p<0.05) and there was a trend for a reduced oxygen uptake at 50% V˙O2peak. Tissue oxygenation improved across exercise intensities and exercise tolerance was greater at 90% V˙O2peak (p<0.05). Rating of perceived exertion, energy levels and cognitive performance were similar between conditions with mental fatigue being evident from 70% V˙O2peak onwards (p<0.05). Dietary nitrate supplementation enhanced short-term endurance exercise performance with concomitant mental fatigue but did not improve cognitive performance post-fatigue.

    AB - Dietary inorganic nitrate supplementation causes physiological effects which may enhance exercise tolerance. However it is not known whether nitrate might alter cognitive function during exercise. In a double-blind, cross-over study, sixteen subjects ingested either nitrate-rich beetroot juice or a placebo and completed a continuous cycle exercise test involving 20min stages at 50% and 70% V˙O2peak and a final stage at 90% V˙O2peak until volitional exhaustion. Cognitive tasks were completed before, during and after exercise. In the dietary nitrate condition: plasma [nitrite] increased (p<0.01), systolic blood pressure decreased (p<0.05) and there was a trend for a reduced oxygen uptake at 50% V˙O2peak. Tissue oxygenation improved across exercise intensities and exercise tolerance was greater at 90% V˙O2peak (p<0.05). Rating of perceived exertion, energy levels and cognitive performance were similar between conditions with mental fatigue being evident from 70% V˙O2peak onwards (p<0.05). Dietary nitrate supplementation enhanced short-term endurance exercise performance with concomitant mental fatigue but did not improve cognitive performance post-fatigue.

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