Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation

François Billaut, Jarrod P. Kerris, Ramon F. Rodriguez, David T. Martin, Christopher J. Gore, David J. Bishop

Research output: Contribution to journalArticle

48 Citations (Scopus)
1 Downloads (Pure)

Abstract

Purpose:To investigate the interaction between the development of peripheral locomotor muscle fatigue, muscle recruitment and performance during repeated-sprint exercise (RSE).Method:In a single-blind, randomised and cross-over design, ten male team-sport athletes performed two RSE (fifteen 5-s cycling sprints interspersed with 25 s of rest; power self-selected) in normoxia and in acute moderate hypoxia (FIO2 0.138). Mechanical work, total electromyographic intensity (summed quadriceps electromyograms, RMSsum) and muscle (vastus lateralis) and pre-fontal cortex near-infrared spectroscopy (NIRS) parameters were calculated for every sprint. Blood lactate concentration ([Lac-]) was measured throughout the protocol. Peripheral quadriceps fatigue was assessed via changes in potentiated quadriceps twitch force (ΔQtw,pot) pre- versus post-exercise in response to supra-maximal magnetic femoral nerve stimulation. The central activation ratio (QCAR) was used to quantify completeness of quadriceps activation.Results:Compared with normoxia, hypoxia reduced arterial oxygen saturation (-13.7%, P=0.001), quadriceps RMSsum (-13.7%, P=0.022), QCAR (-3.3%, P=0.041) and total mechanical work (-8.3%, P=0.019). However, the magnitude of quadriceps fatigue induced by RSE was similar in the two conditions (ΔQtw,pot: -53.5% and -55.1%, P=0.71). The lower cycling performance in hypoxia occurred despite similar metabolic (muscle NIRS parameters and blood [Lac-]) and functional (twitch and M-wave) muscle states.Conclusion:Results suggest that the central nervous system regulates quadriceps muscle recruitment and, thereby, performance to limit the development of muscle fatigue during intermittent, short sprints. This finding highlights the complex interaction between muscular perturbations and neural adjustments during sprint exercise, and further supports the presence of pacing during intermittent sprint exercise.

Original languageEnglish
Article numbere77297
Number of pages12
JournalPLoS One
Volume8
Issue number10
DOIs
Publication statusPublished - 14 Oct 2013
Externally publishedYes

Fingerprint

Muscle
exercise
Exercise
Muscles
Muscle Fatigue
Near-Infrared Spectroscopy
Quadriceps Muscle
muscles
muscle fatigue
Fatigue
hypoxia
Lactic Acid
Fatigue of materials
normoxia
near-infrared spectroscopy
Near infrared spectroscopy
Femoral Nerve
lactates
Electromyography
Athletes

Cite this

Billaut, F., Kerris, J. P., Rodriguez, R. F., Martin, D. T., Gore, C. J., & Bishop, D. J. (2013). Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation. PLoS One, 8(10), [e77297]. https://doi.org/10.1371/journal.pone.0077297
Billaut, François ; Kerris, Jarrod P. ; Rodriguez, Ramon F. ; Martin, David T. ; Gore, Christopher J. ; Bishop, David J. / Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation. In: PLoS One. 2013 ; Vol. 8, No. 10.
@article{38a4017a6df54eb790dcf706193ea0a0,
title = "Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation",
abstract = "Purpose:To investigate the interaction between the development of peripheral locomotor muscle fatigue, muscle recruitment and performance during repeated-sprint exercise (RSE).Method:In a single-blind, randomised and cross-over design, ten male team-sport athletes performed two RSE (fifteen 5-s cycling sprints interspersed with 25 s of rest; power self-selected) in normoxia and in acute moderate hypoxia (FIO2 0.138). Mechanical work, total electromyographic intensity (summed quadriceps electromyograms, RMSsum) and muscle (vastus lateralis) and pre-fontal cortex near-infrared spectroscopy (NIRS) parameters were calculated for every sprint. Blood lactate concentration ([Lac-]) was measured throughout the protocol. Peripheral quadriceps fatigue was assessed via changes in potentiated quadriceps twitch force (ΔQtw,pot) pre- versus post-exercise in response to supra-maximal magnetic femoral nerve stimulation. The central activation ratio (QCAR) was used to quantify completeness of quadriceps activation.Results:Compared with normoxia, hypoxia reduced arterial oxygen saturation (-13.7{\%}, P=0.001), quadriceps RMSsum (-13.7{\%}, P=0.022), QCAR (-3.3{\%}, P=0.041) and total mechanical work (-8.3{\%}, P=0.019). However, the magnitude of quadriceps fatigue induced by RSE was similar in the two conditions (ΔQtw,pot: -53.5{\%} and -55.1{\%}, P=0.71). The lower cycling performance in hypoxia occurred despite similar metabolic (muscle NIRS parameters and blood [Lac-]) and functional (twitch and M-wave) muscle states.Conclusion:Results suggest that the central nervous system regulates quadriceps muscle recruitment and, thereby, performance to limit the development of muscle fatigue during intermittent, short sprints. This finding highlights the complex interaction between muscular perturbations and neural adjustments during sprint exercise, and further supports the presence of pacing during intermittent sprint exercise.",
author = "Fran{\cc}ois Billaut and Kerris, {Jarrod P.} and Rodriguez, {Ramon F.} and Martin, {David T.} and Gore, {Christopher J.} and Bishop, {David J.}",
year = "2013",
month = "10",
day = "14",
doi = "10.1371/journal.pone.0077297",
language = "English",
volume = "8",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "10",

}

Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation. / Billaut, François; Kerris, Jarrod P.; Rodriguez, Ramon F.; Martin, David T.; Gore, Christopher J.; Bishop, David J.

In: PLoS One, Vol. 8, No. 10, e77297, 14.10.2013.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Interaction of Central and Peripheral Factors during Repeated Sprints at Different Levels of Arterial O2 Saturation

AU - Billaut, François

AU - Kerris, Jarrod P.

AU - Rodriguez, Ramon F.

AU - Martin, David T.

AU - Gore, Christopher J.

AU - Bishop, David J.

PY - 2013/10/14

Y1 - 2013/10/14

N2 - Purpose:To investigate the interaction between the development of peripheral locomotor muscle fatigue, muscle recruitment and performance during repeated-sprint exercise (RSE).Method:In a single-blind, randomised and cross-over design, ten male team-sport athletes performed two RSE (fifteen 5-s cycling sprints interspersed with 25 s of rest; power self-selected) in normoxia and in acute moderate hypoxia (FIO2 0.138). Mechanical work, total electromyographic intensity (summed quadriceps electromyograms, RMSsum) and muscle (vastus lateralis) and pre-fontal cortex near-infrared spectroscopy (NIRS) parameters were calculated for every sprint. Blood lactate concentration ([Lac-]) was measured throughout the protocol. Peripheral quadriceps fatigue was assessed via changes in potentiated quadriceps twitch force (ΔQtw,pot) pre- versus post-exercise in response to supra-maximal magnetic femoral nerve stimulation. The central activation ratio (QCAR) was used to quantify completeness of quadriceps activation.Results:Compared with normoxia, hypoxia reduced arterial oxygen saturation (-13.7%, P=0.001), quadriceps RMSsum (-13.7%, P=0.022), QCAR (-3.3%, P=0.041) and total mechanical work (-8.3%, P=0.019). However, the magnitude of quadriceps fatigue induced by RSE was similar in the two conditions (ΔQtw,pot: -53.5% and -55.1%, P=0.71). The lower cycling performance in hypoxia occurred despite similar metabolic (muscle NIRS parameters and blood [Lac-]) and functional (twitch and M-wave) muscle states.Conclusion:Results suggest that the central nervous system regulates quadriceps muscle recruitment and, thereby, performance to limit the development of muscle fatigue during intermittent, short sprints. This finding highlights the complex interaction between muscular perturbations and neural adjustments during sprint exercise, and further supports the presence of pacing during intermittent sprint exercise.

AB - Purpose:To investigate the interaction between the development of peripheral locomotor muscle fatigue, muscle recruitment and performance during repeated-sprint exercise (RSE).Method:In a single-blind, randomised and cross-over design, ten male team-sport athletes performed two RSE (fifteen 5-s cycling sprints interspersed with 25 s of rest; power self-selected) in normoxia and in acute moderate hypoxia (FIO2 0.138). Mechanical work, total electromyographic intensity (summed quadriceps electromyograms, RMSsum) and muscle (vastus lateralis) and pre-fontal cortex near-infrared spectroscopy (NIRS) parameters were calculated for every sprint. Blood lactate concentration ([Lac-]) was measured throughout the protocol. Peripheral quadriceps fatigue was assessed via changes in potentiated quadriceps twitch force (ΔQtw,pot) pre- versus post-exercise in response to supra-maximal magnetic femoral nerve stimulation. The central activation ratio (QCAR) was used to quantify completeness of quadriceps activation.Results:Compared with normoxia, hypoxia reduced arterial oxygen saturation (-13.7%, P=0.001), quadriceps RMSsum (-13.7%, P=0.022), QCAR (-3.3%, P=0.041) and total mechanical work (-8.3%, P=0.019). However, the magnitude of quadriceps fatigue induced by RSE was similar in the two conditions (ΔQtw,pot: -53.5% and -55.1%, P=0.71). The lower cycling performance in hypoxia occurred despite similar metabolic (muscle NIRS parameters and blood [Lac-]) and functional (twitch and M-wave) muscle states.Conclusion:Results suggest that the central nervous system regulates quadriceps muscle recruitment and, thereby, performance to limit the development of muscle fatigue during intermittent, short sprints. This finding highlights the complex interaction between muscular perturbations and neural adjustments during sprint exercise, and further supports the presence of pacing during intermittent sprint exercise.

UR - http://www.scopus.com/inward/record.url?scp=84885400004&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0077297

DO - 10.1371/journal.pone.0077297

M3 - Article

VL - 8

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 10

M1 - e77297

ER -