Intervention strategies for seasonal and emerging respiratory viruses with drugs and vaccines targeting viral surface glycoproteins

Ralph A. Tripp; John Stambas

doi:10.3390/v13040625

Intervention strategies for seasonal and emerging respiratory viruses with drugs and vaccines targeting viral surface glycoproteins

Ralph A. Tripp, John Stambas

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

38 Downloads (Pure)

Abstract

Vaccines and therapeutics targeting viral surface glycoproteins are a major component of disease prevention for respiratory viral diseases. Over the years, vaccines have proven to be the most successful intervention for preventing disease. Technological advances in vaccine platforms that focus on viral surface glycoproteins have provided solutions for current and emerging pathogens like SARS-CoV-2, and our understanding of the structural basis for antibody neutralization is guiding the selection of other vaccine targets for respiratory viruses like RSV. This review discusses the role of viral surface glycoproteins in disease intervention approaches.

Original language	English
Article number	625
Pages (from-to)	1-8
Number of pages	8
Journal	Viruses
Volume	13
Issue number	4
DOIs	https://doi.org/10.3390/v13040625
Publication status	Published - Apr 2021
Externally published	Yes

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10.3390/v13040625Licence: CC BY

ArticleFinal published version, 237 KBLicence: CC BY

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title = "Intervention strategies for seasonal and emerging respiratory viruses with drugs and vaccines targeting viral surface glycoproteins",

abstract = "Vaccines and therapeutics targeting viral surface glycoproteins are a major component of disease prevention for respiratory viral diseases. Over the years, vaccines have proven to be the most successful intervention for preventing disease. Technological advances in vaccine platforms that focus on viral surface glycoproteins have provided solutions for current and emerging pathogens like SARS-CoV-2, and our understanding of the structural basis for antibody neutralization is guiding the selection of other vaccine targets for respiratory viruses like RSV. This review discusses the role of viral surface glycoproteins in disease intervention approaches.",

keywords = "Respiratory syncytial virus, Respiratory virus, RSV, SARS-CoV-2, Therapeutics, Vaccines",

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AB - Vaccines and therapeutics targeting viral surface glycoproteins are a major component of disease prevention for respiratory viral diseases. Over the years, vaccines have proven to be the most successful intervention for preventing disease. Technological advances in vaccine platforms that focus on viral surface glycoproteins have provided solutions for current and emerging pathogens like SARS-CoV-2, and our understanding of the structural basis for antibody neutralization is guiding the selection of other vaccine targets for respiratory viruses like RSV. This review discusses the role of viral surface glycoproteins in disease intervention approaches.

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KW - Respiratory virus

KW - RSV

KW - SARS-CoV-2

KW - Therapeutics

KW - Vaccines

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ER -

Intervention strategies for seasonal and emerging respiratory viruses with drugs and vaccines targeting viral surface glycoproteins

Abstract

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