Intrinsic functional deficits associated with increased risk of ankle injuries: a systematic review with meta-analysis

Jeremy WITCHALLS, Peter Blanch, Gordon WADDINGTON, Roger Adams

Research output: Contribution to journalArticlepeer-review

110 Citations (Scopus)


Background A history of ankle injury is known to be associated with an increased risk of future injuries. Prevention of a first-time injury to an ankle will also prevent subsequent re-injury; yet these participants are often overlooked in reports of preventive testing. Determining the functional deficits which promote injury risk in all ankles, through studies inclusive of previously injured and never injured ankles, will enable training to be directed at improving known deficits in all sports participants. Objective To review studies investigating the measurement of intrinsic functions in healthy ankles and assess their predictive value for injury. Method Systematic review and meta-analysis of journal articles from selected electronic databases. Using all papers that included sufficient data for extraction in any paradigm, the authors pooled results for measures of strength, postural control, proprioception, muscle reaction time in response to perturbation, range of movement and ligament stability. Results Thirteen papers were found with adequate data reporting to allow calculation of pooled standardised mean difference (SMD) or pooled RR. The following are all associated with an increased risk of ankle injury: higher postural sway (SMD=0.693, 95% CI=0.151 to 1.235, p=0.012), being in the lower postural stability group (RR=2.06, 95% CI=1.364 to 3.111, p=0.001), lower inversion proprioception (0.573, 0.244 to 0.902,
Original languageEnglish
Pages (from-to)515-523
Number of pages9
JournalBritish Journal of Sports Medicine
Issue number7
Publication statusPublished - 2011


Dive into the research topics of 'Intrinsic functional deficits associated with increased risk of ankle injuries: a systematic review with meta-analysis'. Together they form a unique fingerprint.

Cite this