Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?

Klaus I. Matthaei, Michael Frese, Caryl E. Hill

Research output: Contribution to journalLetter

6 Citations (Scopus)

Abstract

We read with interest the manuscript by Ward et al. (1) in PNAS in which selective disruption of the p150 isoform, but not the p110 isoform, of the RNA editing enzyme Adenosine Deaminase 1 (ADAR1) was reported to cause early embryonic lethality.
Original languageEnglish
Article number108(12)E43
JournalProceedings of the National Academy of Sciences of the United States of America
Volume108
Issue number12
DOIs
Publication statusPublished - 22 Mar 2011

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RNA Editing
RNA Isoforms
Adenosine Deaminase
Protein Isoforms
Manuscripts
Enzymes

Cite this

@article{34abe16105db43789549f64cd0ab4d3a,
title = "Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?",
abstract = "We read with interest the manuscript by Ward et al. (1) in PNAS in which selective disruption of the p150 isoform, but not the p110 isoform, of the RNA editing enzyme Adenosine Deaminase 1 (ADAR1) was reported to cause early embryonic lethality.",
keywords = "p150 isoform, Adenosine Deaminase 1, embryonic lethality",
author = "Matthaei, {Klaus I.} and Michael Frese and Hill, {Caryl E.}",
year = "2011",
month = "3",
day = "22",
doi = "10.1073/pnas.1100419108",
language = "English",
volume = "108",
journal = "National Academy of Sciences. Proceedings",
issn = "0027-8424",
number = "12",

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TY - JOUR

T1 - Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?

AU - Matthaei, Klaus I.

AU - Frese, Michael

AU - Hill, Caryl E.

PY - 2011/3/22

Y1 - 2011/3/22

N2 - We read with interest the manuscript by Ward et al. (1) in PNAS in which selective disruption of the p150 isoform, but not the p110 isoform, of the RNA editing enzyme Adenosine Deaminase 1 (ADAR1) was reported to cause early embryonic lethality.

AB - We read with interest the manuscript by Ward et al. (1) in PNAS in which selective disruption of the p150 isoform, but not the p110 isoform, of the RNA editing enzyme Adenosine Deaminase 1 (ADAR1) was reported to cause early embryonic lethality.

KW - p150 isoform

KW - Adenosine Deaminase 1

KW - embryonic lethality

UR - http://www.scopus.com/inward/record.url?scp=79953167200&partnerID=8YFLogxK

U2 - 10.1073/pnas.1100419108

DO - 10.1073/pnas.1100419108

M3 - Letter

VL - 108

JO - National Academy of Sciences. Proceedings

JF - National Academy of Sciences. Proceedings

SN - 0027-8424

IS - 12

M1 - 108(12)E43

ER -