TY - JOUR
T1 - Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
AU - Viana, Patrik F.
AU - Ezaz, Tariq
AU - de Bello Cioffi, Marcelo
AU - Liehr, Thomas
AU - Al-Rikabi, Ahmed
AU - Goll, Leonardo G.
AU - Rocha, Anderson M.
AU - Feldberg, Eliana
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages of degeneration. However, undifferentiated sex chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed that several genes share ancestry among X, Y and Z chromosomes, implying that XY and ZW may have undergone transitions during serpent’s evolution. In this study, we performed a comparative cytogenetic analysis to identify homologies of sex chromosomes across ancestral (Henophidia) and more recent (Caenophidia) snakes. Our analysis suggests that, despite ~ 85 myr of independent evolution, henophidians and caenophidians retained conserved synteny over much of their genomes. However, our findings allowed us to discover that ancestral and recent lineages of snakes do not share the same sex chromosome and followed distinct pathways for sex chromosomes evolution.
AB - Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages of degeneration. However, undifferentiated sex chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed that several genes share ancestry among X, Y and Z chromosomes, implying that XY and ZW may have undergone transitions during serpent’s evolution. In this study, we performed a comparative cytogenetic analysis to identify homologies of sex chromosomes across ancestral (Henophidia) and more recent (Caenophidia) snakes. Our analysis suggests that, despite ~ 85 myr of independent evolution, henophidians and caenophidians retained conserved synteny over much of their genomes. However, our findings allowed us to discover that ancestral and recent lineages of snakes do not share the same sex chromosome and followed distinct pathways for sex chromosomes evolution.
UR - http://www.scopus.com/inward/record.url?scp=85088592756&partnerID=8YFLogxK
U2 - 10.1038/s41598-020-69349-5
DO - 10.1038/s41598-020-69349-5
M3 - Article
C2 - 32719365
AN - SCOPUS:85088592756
SN - 2045-2322
VL - 10
SP - 1
EP - 14
JO - Scientific Reports
JF - Scientific Reports
M1 - 12499
ER -