It has been a distinct honor to lead Seminars in Oncology Nursing as the Editor-in-Chief throughout the COVID-19 pandemic and conclude my 3-year term with this special issue focused on leadership in oncology nursing. During my time of serving as the editor in chief of Seminars in Oncology Nursing I have observed an impressive rise in oncology nursing research scholarship contributions. Our journal is now ranked in the top 10 nursing journals globally, moved from a quartile four to a top quartile one journal ranking, with rapid rise in impact factor (3.5 rating) during my time serving for this journal. Our author contributions have underscored that nursing leadership is exposed to various organizational, scientific, political, and economic demand. Leadership practices among our oncology nursing workforce can positively or negatively influence outcomes for organizations, providers, and ultimately patients. In this issue, we discuss many important topics related to nursing leadership in oncology that have not been often addressed in the prior peer-reviewed literature.