Liquid Chromatography

Chiral

V. R. Meyer, Diana IBRAHIM, Ashraf GHANEM

Research output: A Conference proceeding or a Chapter in BookEntry for encyclopedia/dictionary

Abstract

Enantioselective separation of enantiomers in liquid chromatography is a tremendous success story. Undoubtedly, there will continuously be significant developments in chiral stationary phases. There will be additional improvements in the immobilization, stability, and efficiency of existing classes of chiral selectors. We may even see the introduction of completely new and exciting classes of chiral selectors, although it is unlikely that this will happen at the same rapid pace of the previous decade. Despite the success of liquid chromatography chiral stationary phases, there remain several types of enantiomers that are not yet easily resolved by this approach.
Original languageEnglish
Title of host publicationEncyclopedia of Analytical Science
EditorsPaul Worsfold, Alan Townshend, Colin Poole, Manuel Miro
PublisherElsevier
Pages12-23
Number of pages11
Volume6
Edition3
ISBN (Electronic)9780081019849
ISBN (Print)9780081019832
DOIs
Publication statusPublished - 15 Feb 2019

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Enantiomers
Liquid chromatography

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Meyer, V. R., IBRAHIM, D., & GHANEM, A. (2019). Liquid Chromatography: Chiral. In P. Worsfold, A. Townshend, C. Poole, & M. Miro (Eds.), Encyclopedia of Analytical Science (3 ed., Vol. 6, pp. 12-23). Elsevier. https://doi.org/10.1016/B978-0-12-409547-2.00286-9
Meyer, V. R. ; IBRAHIM, Diana ; GHANEM, Ashraf. / Liquid Chromatography : Chiral. Encyclopedia of Analytical Science. editor / Paul Worsfold ; Alan Townshend ; Colin Poole ; Manuel Miro. Vol. 6 3. ed. Elsevier, 2019. pp. 12-23
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Meyer, VR, IBRAHIM, D & GHANEM, A 2019, Liquid Chromatography: Chiral. in P Worsfold, A Townshend, C Poole & M Miro (eds), Encyclopedia of Analytical Science. 3 edn, vol. 6, Elsevier, pp. 12-23. https://doi.org/10.1016/B978-0-12-409547-2.00286-9

Liquid Chromatography : Chiral. / Meyer, V. R.; IBRAHIM, Diana; GHANEM, Ashraf.

Encyclopedia of Analytical Science. ed. / Paul Worsfold; Alan Townshend; Colin Poole; Manuel Miro. Vol. 6 3. ed. Elsevier, 2019. p. 12-23.

Research output: A Conference proceeding or a Chapter in BookEntry for encyclopedia/dictionary

TY - CHAP

T1 - Liquid Chromatography

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N2 - Enantioselective separation of enantiomers in liquid chromatography is a tremendous success story. Undoubtedly, there will continuously be significant developments in chiral stationary phases. There will be additional improvements in the immobilization, stability, and efficiency of existing classes of chiral selectors. We may even see the introduction of completely new and exciting classes of chiral selectors, although it is unlikely that this will happen at the same rapid pace of the previous decade. Despite the success of liquid chromatography chiral stationary phases, there remain several types of enantiomers that are not yet easily resolved by this approach.

AB - Enantioselective separation of enantiomers in liquid chromatography is a tremendous success story. Undoubtedly, there will continuously be significant developments in chiral stationary phases. There will be additional improvements in the immobilization, stability, and efficiency of existing classes of chiral selectors. We may even see the introduction of completely new and exciting classes of chiral selectors, although it is unlikely that this will happen at the same rapid pace of the previous decade. Despite the success of liquid chromatography chiral stationary phases, there remain several types of enantiomers that are not yet easily resolved by this approach.

KW - Chiral additives

KW - Chiral porous materials

KW - Chiral stationary phases

KW - Chiroptical detection

KW - Core shell

KW - Derivatization

KW - Diastereosiomers

KW - Fully porous particles

KW - Liquid chromatography

KW - Sub-2 micron

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DO - 10.1016/B978-0-12-409547-2.00286-9

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VL - 6

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BT - Encyclopedia of Analytical Science

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A2 - Townshend, Alan

A2 - Poole, Colin

A2 - Miro, Manuel

PB - Elsevier

ER -

Meyer VR, IBRAHIM D, GHANEM A. Liquid Chromatography: Chiral. In Worsfold P, Townshend A, Poole C, Miro M, editors, Encyclopedia of Analytical Science. 3 ed. Vol. 6. Elsevier. 2019. p. 12-23 https://doi.org/10.1016/B978-0-12-409547-2.00286-9