Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research

Michelle Nelson, Steve Su, Suresh Mahalingam

    Research output: Contribution to journalEditorial

    1 Citation (Scopus)

    Abstract

    Chikungunya virus (CHIKV) was first isolated in Tanzania in 1953. Since then, CHIKV outbreaks have occurred sporadically in Sub-Saharan Africa, southeast Asia and India. Most recently, in 2005/2006, a CHIKV outbreak was reported in a number of islands in the western Indian Ocean, which has since spread into India, giving rise to the largest CHIKV epidemic on record. Reports of CHIKV cases in Italy, a more temperate environment, have suggested the potential for this virus to spread worldwide. CHIKV, an Alphavirus belonging to the Togaviridae family, is maintained by transmission cycles between mosquito vectors and vertebrate hosts. Whilst CHIKV disease is generally not fatal, it can cause debilitating symptoms including fever, rash, headache, myalgia and arthralgia. Some more severe cases have been described, for example, in neonates where infection has been found to involve the CNS. As yet, there are no specific treatments available for CHIKV disease, although analgesics and nonsteroidal anti-inflammatory drugs can be given for symptomatic relief.
    Original languageEnglish
    Pages (from-to)509-511
    Number of pages3
    JournalFuture Virology
    Volume3
    Issue number6
    Publication statusPublished - 2008

    Fingerprint

    Ross River virus
    Chikungunya virus
    Virus Diseases
    Research
    Disease Outbreaks
    India
    Togaviridae
    Alphavirus
    Indian Ocean
    Southeastern Asia
    Tanzania
    Africa South of the Sahara
    Myalgia
    Arthralgia
    Non-Steroidal Anti-Inflammatory Agents
    Exanthema
    Islands
    Italy
    Headache
    Vertebrates

    Cite this

    Nelson, M., Su, S., & Mahalingam, S. (2008). Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research. Future Virology, 3(6), 509-511.
    Nelson, Michelle ; Su, Steve ; Mahalingam, Suresh. / Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research. In: Future Virology. 2008 ; Vol. 3, No. 6. pp. 509-511.
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    title = "Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research",
    abstract = "Chikungunya virus (CHIKV) was first isolated in Tanzania in 1953. Since then, CHIKV outbreaks have occurred sporadically in Sub-Saharan Africa, southeast Asia and India. Most recently, in 2005/2006, a CHIKV outbreak was reported in a number of islands in the western Indian Ocean, which has since spread into India, giving rise to the largest CHIKV epidemic on record. Reports of CHIKV cases in Italy, a more temperate environment, have suggested the potential for this virus to spread worldwide. CHIKV, an Alphavirus belonging to the Togaviridae family, is maintained by transmission cycles between mosquito vectors and vertebrate hosts. Whilst CHIKV disease is generally not fatal, it can cause debilitating symptoms including fever, rash, headache, myalgia and arthralgia. Some more severe cases have been described, for example, in neonates where infection has been found to involve the CNS. As yet, there are no specific treatments available for CHIKV disease, although analgesics and nonsteroidal anti-inflammatory drugs can be given for symptomatic relief.",
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    Nelson, M, Su, S & Mahalingam, S 2008, 'Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research', Future Virology, vol. 3, no. 6, pp. 509-511.

    Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research. / Nelson, Michelle; Su, Steve; Mahalingam, Suresh.

    In: Future Virology, Vol. 3, No. 6, 2008, p. 509-511.

    Research output: Contribution to journalEditorial

    TY - JOUR

    T1 - Mechanisms of Chikungunya Virus Disease Informed by Ross River Virus Research

    AU - Nelson, Michelle

    AU - Su, Steve

    AU - Mahalingam, Suresh

    PY - 2008

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    AB - Chikungunya virus (CHIKV) was first isolated in Tanzania in 1953. Since then, CHIKV outbreaks have occurred sporadically in Sub-Saharan Africa, southeast Asia and India. Most recently, in 2005/2006, a CHIKV outbreak was reported in a number of islands in the western Indian Ocean, which has since spread into India, giving rise to the largest CHIKV epidemic on record. Reports of CHIKV cases in Italy, a more temperate environment, have suggested the potential for this virus to spread worldwide. CHIKV, an Alphavirus belonging to the Togaviridae family, is maintained by transmission cycles between mosquito vectors and vertebrate hosts. Whilst CHIKV disease is generally not fatal, it can cause debilitating symptoms including fever, rash, headache, myalgia and arthralgia. Some more severe cases have been described, for example, in neonates where infection has been found to involve the CNS. As yet, there are no specific treatments available for CHIKV disease, although analgesics and nonsteroidal anti-inflammatory drugs can be given for symptomatic relief.

    M3 - Editorial

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    SP - 509

    EP - 511

    JO - Future Virology

    JF - Future Virology

    SN - 1746-0794

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