Molecular imprinting of a small substituted phenol of biological importance

Miruna Petcu; Janine Cooney; Christian Cook; Denis Lauren; Peter Schaare; Pat Holland

doi:10.1016/S0003-2670(00)01354-4

Molecular imprinting of a small substituted phenol of biological importance

Miruna Petcu, Janine Cooney, Christian Cook, Denis Lauren, Peter Schaare, Pat Holland

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A polymer capable of recognising small phenolic molecules is described. Analysis based on batch binding experiments followed by HPLC was used to determine propofol concentration in different test solutions. Polymer particle size and contact time between propofol test solutions and polymers were modified to yield a fast and reliable system for propofol detection. The polymer thus synthesised had little cross-reactivity when tested against other structurally related phenols.

Original language	English
Pages (from-to)	49-55
Number of pages	7
Journal	Analytica Chimica Acta
Volume	435
Issue number	1
DOIs	https://doi.org/10.1016/S0003-2670(00)01354-4
Publication status	Published - 2001
Externally published	Yes

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10.1016/S0003-2670(00)01354-4

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title = "Molecular imprinting of a small substituted phenol of biological importance",

abstract = "A polymer capable of recognising small phenolic molecules is described. Analysis based on batch binding experiments followed by HPLC was used to determine propofol concentration in different test solutions. Polymer particle size and contact time between propofol test solutions and polymers were modified to yield a fast and reliable system for propofol detection. The polymer thus synthesised had little cross-reactivity when tested against other structurally related phenols.",

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AU - Cooney, Janine

AU - Cook, Christian

AU - Lauren, Denis

AU - Schaare, Peter

AU - Holland, Pat

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AB - A polymer capable of recognising small phenolic molecules is described. Analysis based on batch binding experiments followed by HPLC was used to determine propofol concentration in different test solutions. Polymer particle size and contact time between propofol test solutions and polymers were modified to yield a fast and reliable system for propofol detection. The polymer thus synthesised had little cross-reactivity when tested against other structurally related phenols.

KW - Anaesthetic

KW - Molecular imprinting

KW - Popofol

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Molecular imprinting of a small substituted phenol of biological importance

Abstract

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