Multiclass microarray gene expression classification based on fusion of correlation features

Girija Chetty, Madhu Chetty

Research output: A Conference proceeding or a Chapter in BookConference contribution

Abstract

In this paper, we propose novel algorithmic models based on fusion of independent and correlated gene features for multiclass microarray gene expression classification. It is possible for genes to get co-expressed via different pathways. Moreover, a gene may or may not be co-active for all samples. In this paper, we approach this problem with a optimal feature selection technique using analysis based on statistical techniques to model the complex interactions between genes. The two different types of correlation modelling techniques based on the cross modal factor analysis (CFA) and canonical correlation analysis (CCA) were examined. The subsequent fusion of CCA/CFA features with principal component analysis (PCA) features at feature-level, and at score-level result in significant enhancement in classification accuracy for different data sets corresponding to multiclass microarray gene expression data.
Original languageEnglish
Title of host publicationProceedings of the 13th International Conference on Information Fusion
Place of PublicationPiscataway, N.J., USA
PublisherIEEE
Pages1-6
Number of pages6
ISBN (Print)9780982443811
Publication statusPublished - 2010
EventFusion 2010: 13th International Conference on Information Fusion - Edinburgh, United Kingdom
Duration: 26 Jul 201029 Jul 2010

Conference

ConferenceFusion 2010: 13th International Conference on Information Fusion
CountryUnited Kingdom
CityEdinburgh
Period26/07/1029/07/10

Fingerprint

Microarrays
Gene expression
Fusion reactions
Genes
Factor analysis
Principal component analysis
Feature extraction

Cite this

Chetty, G., & Chetty, M. (2010). Multiclass microarray gene expression classification based on fusion of correlation features. In Proceedings of the 13th International Conference on Information Fusion (pp. 1-6). Piscataway, N.J., USA: IEEE.
Chetty, Girija ; Chetty, Madhu. / Multiclass microarray gene expression classification based on fusion of correlation features. Proceedings of the 13th International Conference on Information Fusion. Piscataway, N.J., USA : IEEE, 2010. pp. 1-6
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Chetty, G & Chetty, M 2010, Multiclass microarray gene expression classification based on fusion of correlation features. in Proceedings of the 13th International Conference on Information Fusion. IEEE, Piscataway, N.J., USA, pp. 1-6, Fusion 2010: 13th International Conference on Information Fusion, Edinburgh, United Kingdom, 26/07/10.

Multiclass microarray gene expression classification based on fusion of correlation features. / Chetty, Girija; Chetty, Madhu.

Proceedings of the 13th International Conference on Information Fusion. Piscataway, N.J., USA : IEEE, 2010. p. 1-6.

Research output: A Conference proceeding or a Chapter in BookConference contribution

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Chetty G, Chetty M. Multiclass microarray gene expression classification based on fusion of correlation features. In Proceedings of the 13th International Conference on Information Fusion. Piscataway, N.J., USA: IEEE. 2010. p. 1-6