TY - JOUR
T1 - Myocardial fibrosis in an veteran endurance athlete
AU - Wilson, Mathew
AU - O'Hanlon, Rory
AU - Prasad, Sanjay
AU - Basavarajaiah, Sandeep
AU - Stephens, Nigel
AU - Senior, Roxy
AU - Shaw, Anthony
AU - Sharma, Sanjay
AU - Whyte, Gregory
PY - 2009/8/17
Y1 - 2009/8/17
N2 - This study reports the cardiac structure and function of a lifelong male endurance athlete, who has run over 148 000 miles, who presented with symptoms of chest discomfort, dyspnoea and loss of competitive running performance. Importantly, the athlete documented several periods of regular intensive endurance activity while suffering with flu-like symptoms. Cardiovascular MRI demonstrated a pattern of late gadolinium enhancement, which indicated myocardial scarring as a result of previous myocarditis. Myocarditis is a non-ischaemic inflammatory disease of the myocardium associated with cardiac dysfunction and arrhythmogenic substrate. The clinical course of viral myocarditis is mostly insidious with limited cardiac inflammation and dysfunction. However, as in the present case, overwhelming inflammation may occur in a subset of patients leading to myocardial fibrosis due to recurrent inflammation.
AB - This study reports the cardiac structure and function of a lifelong male endurance athlete, who has run over 148 000 miles, who presented with symptoms of chest discomfort, dyspnoea and loss of competitive running performance. Importantly, the athlete documented several periods of regular intensive endurance activity while suffering with flu-like symptoms. Cardiovascular MRI demonstrated a pattern of late gadolinium enhancement, which indicated myocardial scarring as a result of previous myocarditis. Myocarditis is a non-ischaemic inflammatory disease of the myocardium associated with cardiac dysfunction and arrhythmogenic substrate. The clinical course of viral myocarditis is mostly insidious with limited cardiac inflammation and dysfunction. However, as in the present case, overwhelming inflammation may occur in a subset of patients leading to myocardial fibrosis due to recurrent inflammation.
UR - http://www.scopus.com/inward/record.url?scp=84896535213&partnerID=8YFLogxK
U2 - 10.1136/bcr.12.2008.1345
DO - 10.1136/bcr.12.2008.1345
M3 - Comment/debate
AN - SCOPUS:84896535213
SN - 1757-790X
SP - 1
EP - 7
JO - BMJ Case Reports
JF - BMJ Case Reports
ER -