Myocardial fibrosis in an veteran endurance athlete

Mathew Wilson, Rory O'Hanlon, Sanjay Prasad, Sandeep Basavarajaiah, Nigel Stephens, Roxy Senior, Anthony Shaw, Sanjay Sharma, Gregory Whyte

Research output: Contribution to journalComment/debate

7 Citations (Scopus)

Abstract

This study reports the cardiac structure and function of a lifelong male endurance athlete, who has run over 148 000 miles, who presented with symptoms of chest discomfort, dyspnoea and loss of competitive running performance. Importantly, the athlete documented several periods of regular intensive endurance activity while suffering with flu-like symptoms. Cardiovascular MRI demonstrated a pattern of late gadolinium enhancement, which indicated myocardial scarring as a result of previous myocarditis. Myocarditis is a non-ischaemic inflammatory disease of the myocardium associated with cardiac dysfunction and arrhythmogenic substrate. The clinical course of viral myocarditis is mostly insidious with limited cardiac inflammation and dysfunction. However, as in the present case, overwhelming inflammation may occur in a subset of patients leading to myocardial fibrosis due to recurrent inflammation.

Original languageEnglish
JournalBMJ Case Reports
DOIs
Publication statusPublished - 17 Aug 2009
Externally publishedYes

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Myocarditis
Veterans
Athletes
Fibrosis
Inflammation
Gadolinium
Dyspnea
Cicatrix
Myocardium
Thorax

Cite this

Wilson, M., O'Hanlon, R., Prasad, S., Basavarajaiah, S., Stephens, N., Senior, R., ... Whyte, G. (2009). Myocardial fibrosis in an veteran endurance athlete. BMJ Case Reports. https://doi.org/10.1136/bcr.12.2008.1345
Wilson, Mathew ; O'Hanlon, Rory ; Prasad, Sanjay ; Basavarajaiah, Sandeep ; Stephens, Nigel ; Senior, Roxy ; Shaw, Anthony ; Sharma, Sanjay ; Whyte, Gregory. / Myocardial fibrosis in an veteran endurance athlete. In: BMJ Case Reports. 2009.
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Wilson, M, O'Hanlon, R, Prasad, S, Basavarajaiah, S, Stephens, N, Senior, R, Shaw, A, Sharma, S & Whyte, G 2009, 'Myocardial fibrosis in an veteran endurance athlete', BMJ Case Reports. https://doi.org/10.1136/bcr.12.2008.1345

Myocardial fibrosis in an veteran endurance athlete. / Wilson, Mathew; O'Hanlon, Rory; Prasad, Sanjay; Basavarajaiah, Sandeep; Stephens, Nigel; Senior, Roxy; Shaw, Anthony; Sharma, Sanjay; Whyte, Gregory.

In: BMJ Case Reports, 17.08.2009.

Research output: Contribution to journalComment/debate

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AB - This study reports the cardiac structure and function of a lifelong male endurance athlete, who has run over 148 000 miles, who presented with symptoms of chest discomfort, dyspnoea and loss of competitive running performance. Importantly, the athlete documented several periods of regular intensive endurance activity while suffering with flu-like symptoms. Cardiovascular MRI demonstrated a pattern of late gadolinium enhancement, which indicated myocardial scarring as a result of previous myocarditis. Myocarditis is a non-ischaemic inflammatory disease of the myocardium associated with cardiac dysfunction and arrhythmogenic substrate. The clinical course of viral myocarditis is mostly insidious with limited cardiac inflammation and dysfunction. However, as in the present case, overwhelming inflammation may occur in a subset of patients leading to myocardial fibrosis due to recurrent inflammation.

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Wilson M, O'Hanlon R, Prasad S, Basavarajaiah S, Stephens N, Senior R et al. Myocardial fibrosis in an veteran endurance athlete. BMJ Case Reports. 2009 Aug 17. https://doi.org/10.1136/bcr.12.2008.1345