New registration algorithm for determining 3D knee kinematics using CT and single-plane fluoroscopy with improved out-of-plane translation accuracy

Jennifer M. Scarvell, Mark R. Pickering, Paul N. Smith

    Research output: Contribution to journalArticle

    24 Citations (Scopus)

    Abstract

    To understand the kinematic effects of surgery, arthroplasty or conservative treatments, a noninvasive system to capture accurate 3D imaging of functional activities in prospective, controlled studies is required. To provide such a technique, a new algorithm was developed to register 3D CT data of normal bones to the same bones in a 2D fluoroscopy frame. The algorithm produces a digitally reconstructed radiograph (DRR) from the CT data and then filters this to produce an edge-enhanced image. The resulting image is then registered with an edge-enhanced version of the fluoroscopy frame using a new similarity measure called Cross-Correlation Residual Entropy (CCRE). The system was evaluated by implanting tantalum beads into three cadaveric knees to act as fiducial markers. The knees were flexed between 08 and 708, and single-plane fluoroscopy data of the knees were acquired. CT data of the femur and tibia were then individually registered to the fluoroscopy images. No significant measurement bias was observed, and the standard deviation of the error in bead positions was 0.38mmfor in-plane translation and 0.42 degrees for rotation. To determine the accuracy of the registration algorithm for out-of-plane translations, fluoroscopy frames were scaled in size by fixed increments; the average standard deviation of the errors for out-ofplane translation was 0.65 mm. The ability to obtain such accurate 3D motion data from a noninvasive technique will enable prospective, longitudinal, and controlled studies of reconstruction surgery, and conservative management of joint pathologies.

    Original languageEnglish
    Pages (from-to)334-340
    Number of pages7
    JournalJournal of Orthopaedic Research
    Volume28
    Issue number3
    DOIs
    Publication statusPublished - Mar 2010

    Fingerprint

    Fluoroscopy
    Biomechanical Phenomena
    Knee
    Fiducial Markers
    Tantalum
    Bone and Bones
    Entropy
    Tibia
    Arthroplasty
    Femur
    Longitudinal Studies
    Joints
    Prospective Studies
    Pathology
    Conservative Treatment

    Cite this

    @article{755e539fcffc44d6b78e60ed800b6064,
    title = "New registration algorithm for determining 3D knee kinematics using CT and single-plane fluoroscopy with improved out-of-plane translation accuracy",
    abstract = "To understand the kinematic effects of surgery, arthroplasty or conservative treatments, a noninvasive system to capture accurate 3D imaging of functional activities in prospective, controlled studies is required. To provide such a technique, a new algorithm was developed to register 3D CT data of normal bones to the same bones in a 2D fluoroscopy frame. The algorithm produces a digitally reconstructed radiograph (DRR) from the CT data and then filters this to produce an edge-enhanced image. The resulting image is then registered with an edge-enhanced version of the fluoroscopy frame using a new similarity measure called Cross-Correlation Residual Entropy (CCRE). The system was evaluated by implanting tantalum beads into three cadaveric knees to act as fiducial markers. The knees were flexed between 08 and 708, and single-plane fluoroscopy data of the knees were acquired. CT data of the femur and tibia were then individually registered to the fluoroscopy images. No significant measurement bias was observed, and the standard deviation of the error in bead positions was 0.38mmfor in-plane translation and 0.42 degrees for rotation. To determine the accuracy of the registration algorithm for out-of-plane translations, fluoroscopy frames were scaled in size by fixed increments; the average standard deviation of the errors for out-ofplane translation was 0.65 mm. The ability to obtain such accurate 3D motion data from a noninvasive technique will enable prospective, longitudinal, and controlled studies of reconstruction surgery, and conservative management of joint pathologies.",
    keywords = "Computed tomography, Fluoroscopy, Knee kinematics, Multimodal image registration, Mutual information",
    author = "Scarvell, {Jennifer M.} and Pickering, {Mark R.} and Smith, {Paul N.}",
    year = "2010",
    month = "3",
    doi = "10.1002/jor.21003",
    language = "English",
    volume = "28",
    pages = "334--340",
    journal = "Journal of Orthopaedic Research",
    issn = "0736-0266",
    publisher = "Wiley-Blackwell",
    number = "3",

    }

    New registration algorithm for determining 3D knee kinematics using CT and single-plane fluoroscopy with improved out-of-plane translation accuracy. / Scarvell, Jennifer M.; Pickering, Mark R.; Smith, Paul N.

    In: Journal of Orthopaedic Research, Vol. 28, No. 3, 03.2010, p. 334-340.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - New registration algorithm for determining 3D knee kinematics using CT and single-plane fluoroscopy with improved out-of-plane translation accuracy

    AU - Scarvell, Jennifer M.

    AU - Pickering, Mark R.

    AU - Smith, Paul N.

    PY - 2010/3

    Y1 - 2010/3

    N2 - To understand the kinematic effects of surgery, arthroplasty or conservative treatments, a noninvasive system to capture accurate 3D imaging of functional activities in prospective, controlled studies is required. To provide such a technique, a new algorithm was developed to register 3D CT data of normal bones to the same bones in a 2D fluoroscopy frame. The algorithm produces a digitally reconstructed radiograph (DRR) from the CT data and then filters this to produce an edge-enhanced image. The resulting image is then registered with an edge-enhanced version of the fluoroscopy frame using a new similarity measure called Cross-Correlation Residual Entropy (CCRE). The system was evaluated by implanting tantalum beads into three cadaveric knees to act as fiducial markers. The knees were flexed between 08 and 708, and single-plane fluoroscopy data of the knees were acquired. CT data of the femur and tibia were then individually registered to the fluoroscopy images. No significant measurement bias was observed, and the standard deviation of the error in bead positions was 0.38mmfor in-plane translation and 0.42 degrees for rotation. To determine the accuracy of the registration algorithm for out-of-plane translations, fluoroscopy frames were scaled in size by fixed increments; the average standard deviation of the errors for out-ofplane translation was 0.65 mm. The ability to obtain such accurate 3D motion data from a noninvasive technique will enable prospective, longitudinal, and controlled studies of reconstruction surgery, and conservative management of joint pathologies.

    AB - To understand the kinematic effects of surgery, arthroplasty or conservative treatments, a noninvasive system to capture accurate 3D imaging of functional activities in prospective, controlled studies is required. To provide such a technique, a new algorithm was developed to register 3D CT data of normal bones to the same bones in a 2D fluoroscopy frame. The algorithm produces a digitally reconstructed radiograph (DRR) from the CT data and then filters this to produce an edge-enhanced image. The resulting image is then registered with an edge-enhanced version of the fluoroscopy frame using a new similarity measure called Cross-Correlation Residual Entropy (CCRE). The system was evaluated by implanting tantalum beads into three cadaveric knees to act as fiducial markers. The knees were flexed between 08 and 708, and single-plane fluoroscopy data of the knees were acquired. CT data of the femur and tibia were then individually registered to the fluoroscopy images. No significant measurement bias was observed, and the standard deviation of the error in bead positions was 0.38mmfor in-plane translation and 0.42 degrees for rotation. To determine the accuracy of the registration algorithm for out-of-plane translations, fluoroscopy frames were scaled in size by fixed increments; the average standard deviation of the errors for out-ofplane translation was 0.65 mm. The ability to obtain such accurate 3D motion data from a noninvasive technique will enable prospective, longitudinal, and controlled studies of reconstruction surgery, and conservative management of joint pathologies.

    KW - Computed tomography

    KW - Fluoroscopy

    KW - Knee kinematics

    KW - Multimodal image registration

    KW - Mutual information

    UR - http://www.scopus.com/inward/record.url?scp=73949122301&partnerID=8YFLogxK

    U2 - 10.1002/jor.21003

    DO - 10.1002/jor.21003

    M3 - Article

    VL - 28

    SP - 334

    EP - 340

    JO - Journal of Orthopaedic Research

    JF - Journal of Orthopaedic Research

    SN - 0736-0266

    IS - 3

    ER -