Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant capacity from Euphorbia tirucalli using response surface methodology

Quan V. Vuong; Chloe D. Goldsmith; Trung Thanh Dang; Van Tang Nguyen; Deep Jyoti Bhuyan; Elham Sadeqzadeh; Christopher J. Scarlett; Michael C. Bowyer

doi:10.3390/antiox3030604

Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant capacity from Euphorbia tirucalli using response surface methodology

Quan V. Vuong, Chloe D. Goldsmith, Trung Thanh Dang, Van Tang Nguyen, Deep Jyoti Bhuyan, Elham Sadeqzadeh, Christopher J. Scarlett, Michael C. Bowyer

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Abstract

Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temperature, time and power effected TPC and antioxidant capacity; however, the effects varied. Ultrasonic power had the strongest influence on TPC; whereas ultrasonic temperature had the greatest impact on antioxidant capacity. Ultrasonic time had the least impact on both TPC and antioxidant capacity. The optimum UAE conditions were determined to be 50 °C, 90 min. and 200 W. Under these conditions, the E. tirucalli leaf extract yielded 2.93 mg GAE/g FW of TPC and exhibited potent antioxidant capacity. These conditions can be utilised for further isolation and purification of phenolic compounds from E. tirucalli leaf.

Original language	English
Pages (from-to)	604-617
Number of pages	14
Journal	Antioxidants
Volume	3
Issue number	3
DOIs	https://doi.org/10.3390/antiox3030604
Publication status	Published - Sept 2014
Externally published	Yes

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@article{d992e6ef22554590ae912931373529d3,

title = "Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant capacity from Euphorbia tirucalli using response surface methodology",

abstract = "Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temperature, time and power effected TPC and antioxidant capacity; however, the effects varied. Ultrasonic power had the strongest influence on TPC; whereas ultrasonic temperature had the greatest impact on antioxidant capacity. Ultrasonic time had the least impact on both TPC and antioxidant capacity. The optimum UAE conditions were determined to be 50 °C, 90 min. and 200 W. Under these conditions, the E. tirucalli leaf extract yielded 2.93 mg GAE/g FW of TPC and exhibited potent antioxidant capacity. These conditions can be utilised for further isolation and purification of phenolic compounds from E. tirucalli leaf.",

keywords = "Antioxidant, Euphorbia tirucalli, Optimization, Phenolic compounds, Response surface methodology, Ultrasonic-assisted extraction",

author = "Vuong, {Quan V.} and Goldsmith, {Chloe D.} and Dang, {Trung Thanh} and Nguyen, {Van Tang} and Bhuyan, {Deep Jyoti} and Elham Sadeqzadeh and Scarlett, {Christopher J.} and Bowyer, {Michael C.}",

note = "Funding Information: The authors would like to acknowledge the following funding support: Ramaciotti Foundation (ES2012/0104); Cancer Australia and Cure Cancer Australia Foundation (1033781). The authors also kindly thank the Vietnamese Government through the Vietnam International Education Development - Ministry of Education and Training (Project 911) and the University of Newcastle for awarding a VIED-TUIT scholarship to VTN and TTD. Publisher Copyright: {\textcopyright} 2014 by the authors; licensee MDPI, Basel, Switzerland.",

year = "2014",

month = sep,

doi = "10.3390/antiox3030604",

language = "English",

volume = "3",

pages = "604--617",

journal = "Antioxidants",

issn = "2076-3921",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "3",

}

TY - JOUR

T1 - Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant capacity from Euphorbia tirucalli using response surface methodology

AU - Vuong, Quan V.

AU - Goldsmith, Chloe D.

AU - Dang, Trung Thanh

AU - Nguyen, Van Tang

AU - Bhuyan, Deep Jyoti

AU - Sadeqzadeh, Elham

AU - Scarlett, Christopher J.

AU - Bowyer, Michael C.

N1 - Funding Information: The authors would like to acknowledge the following funding support: Ramaciotti Foundation (ES2012/0104); Cancer Australia and Cure Cancer Australia Foundation (1033781). The authors also kindly thank the Vietnamese Government through the Vietnam International Education Development - Ministry of Education and Training (Project 911) and the University of Newcastle for awarding a VIED-TUIT scholarship to VTN and TTD. Publisher Copyright: © 2014 by the authors; licensee MDPI, Basel, Switzerland.

PY - 2014/9

Y1 - 2014/9

N2 - Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temperature, time and power effected TPC and antioxidant capacity; however, the effects varied. Ultrasonic power had the strongest influence on TPC; whereas ultrasonic temperature had the greatest impact on antioxidant capacity. Ultrasonic time had the least impact on both TPC and antioxidant capacity. The optimum UAE conditions were determined to be 50 °C, 90 min. and 200 W. Under these conditions, the E. tirucalli leaf extract yielded 2.93 mg GAE/g FW of TPC and exhibited potent antioxidant capacity. These conditions can be utilised for further isolation and purification of phenolic compounds from E. tirucalli leaf.

AB - Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temperature, time and power effected TPC and antioxidant capacity; however, the effects varied. Ultrasonic power had the strongest influence on TPC; whereas ultrasonic temperature had the greatest impact on antioxidant capacity. Ultrasonic time had the least impact on both TPC and antioxidant capacity. The optimum UAE conditions were determined to be 50 °C, 90 min. and 200 W. Under these conditions, the E. tirucalli leaf extract yielded 2.93 mg GAE/g FW of TPC and exhibited potent antioxidant capacity. These conditions can be utilised for further isolation and purification of phenolic compounds from E. tirucalli leaf.

KW - Antioxidant

KW - Euphorbia tirucalli

KW - Optimization

KW - Phenolic compounds

KW - Response surface methodology

KW - Ultrasonic-assisted extraction

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EP - 617

JO - Antioxidants

JF - Antioxidants

IS - 3

ER -

Optimisation of ultrasound-assisted extraction conditions for phenolic content and antioxidant capacity from Euphorbia tirucalli using response surface methodology

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