PCR for detection of oseltamivir resistance mutation in influenza A(H7N9) virus

Wei Wang, Zhigang Song, Wencai Guan, Yi Liu, Xiaonan Zhang, Lei Xu, Jianhua Li, Zhenghong Yuan, Yunwen Hu

Research output: Contribution to journalShort surveypeer-review

10 Citations (Scopus)

Abstract

Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.

Original languageEnglish
Pages (from-to)847-849
Number of pages3
JournalEmerging Infectious Diseases
Volume20
Issue number5
DOIs
Publication statusPublished - May 2014
Externally publishedYes

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