@article{0e5e331cfc1848f1a838b3375aa5d295,
title = "PCR for detection of oseltamivir resistance mutation in influenza A(H7N9) virus",
abstract = "Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens. ",
keywords = "Antiviral Agents/pharmacology, Drug Resistance, Viral/genetics, Humans, Influenza A Virus, H7N9 Subtype/drug effects, Influenza, Human/drug therapy, Mutation, Neuraminidase/genetics, Oseltamivir/pharmacology, Polymerase Chain Reaction, Viral Proteins/genetics",
author = "Wei Wang and Zhigang Song and Wencai Guan and Yi Liu and Xiaonan Zhang and Lei Xu and Jianhua Li and Zhenghong Yuan and Yunwen Hu",
year = "2014",
month = may,
doi = "10.3201/eid2005.131364",
language = "English",
volume = "20",
pages = "847--849",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "5",
}