Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents

the International Children’s Accelerometry Database (ICAD) Collaborators, Rachel Davey

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives: To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers. Methods: A cross-sectional study using the International Children’s Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4–18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association. Results: Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a −0.027 (95% CI: −0.039 to −0.014) standard deviations lower composite risk score, and a −0.064 (95% CI: −0.09 to −0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: −0.002 (95% CI: −0.005 to 0.0005) standard deviations for the composite risk score, and −0.005 (95% CI: −0.012 to 0.002) kg/m2 for BMI). Conclusions: Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.
Original languageEnglish
Pages (from-to)1639-1650
Number of pages12
JournalInternational Journal of Obesity
Volume42
Issue number9
DOIs
Publication statusPublished - 2018

Fingerprint

Exercise
Accelerometry
Linear Models
Adiposity
Waist Circumference
Body Mass Index
Cross-Sectional Studies
Biomarkers
Databases
Blood Pressure

Cite this

the International Children’s Accelerometry Database (ICAD) Collaborators ; Davey, Rachel. / Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents. In: International Journal of Obesity. 2018 ; Vol. 42, No. 9. pp. 1639-1650.
@article{655f6ee621824838a6d67f6ac0f6e2f2,
title = "Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents",
abstract = "Objectives: To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers. Methods: A cross-sectional study using the International Children’s Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4–18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association. Results: Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a −0.027 (95{\%} CI: −0.039 to −0.014) standard deviations lower composite risk score, and a −0.064 (95{\%} CI: −0.09 to −0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: −0.002 (95{\%} CI: −0.005 to 0.0005) standard deviations for the composite risk score, and −0.005 (95{\%} CI: −0.012 to 0.002) kg/m2 for BMI). Conclusions: Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.",
author = "{the International Children’s Accelerometry Database (ICAD) Collaborators} and Jakob Tarp and Abbey Child and Tom White and Kate Westgate and Anna Bugge and Anders Gr{\o}ntved and Niels Wedderkopp and Andersen, {Lars B.} and Greet Cardon and Rachel Davey and Janz, {Kathleen F.} and Susi Kriemler and Kate Northstone and Page, {Angie S.} and Puder, {Jardena J.} and Reilly, {John J.} and Sardinha, {Luis B.} and {van Sluijs}, {Esther M.F.} and Ulf Ekelund and Katrien Wijndaele and S{\o}ren Brage",
year = "2018",
doi = "10.1038/s41366-018-0152-8",
language = "English",
volume = "42",
pages = "1639--1650",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "Nature Publishing Group",
number = "9",

}

Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents. / the International Children’s Accelerometry Database (ICAD) Collaborators ; Davey, Rachel.

In: International Journal of Obesity, Vol. 42, No. 9, 2018, p. 1639-1650.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Physical activity intensity, bout-duration, and cardiometabolic risk markers in children and adolescents

AU - the International Children’s Accelerometry Database (ICAD) Collaborators

AU - Tarp, Jakob

AU - Child, Abbey

AU - White, Tom

AU - Westgate, Kate

AU - Bugge, Anna

AU - Grøntved, Anders

AU - Wedderkopp, Niels

AU - Andersen, Lars B.

AU - Cardon, Greet

AU - Davey, Rachel

AU - Janz, Kathleen F.

AU - Kriemler, Susi

AU - Northstone, Kate

AU - Page, Angie S.

AU - Puder, Jardena J.

AU - Reilly, John J.

AU - Sardinha, Luis B.

AU - van Sluijs, Esther M.F.

AU - Ekelund, Ulf

AU - Wijndaele, Katrien

AU - Brage, Søren

PY - 2018

Y1 - 2018

N2 - Objectives: To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers. Methods: A cross-sectional study using the International Children’s Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4–18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association. Results: Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a −0.027 (95% CI: −0.039 to −0.014) standard deviations lower composite risk score, and a −0.064 (95% CI: −0.09 to −0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: −0.002 (95% CI: −0.005 to 0.0005) standard deviations for the composite risk score, and −0.005 (95% CI: −0.012 to 0.002) kg/m2 for BMI). Conclusions: Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.

AB - Objectives: To determine the role of physical activity intensity and bout-duration in modulating associations between physical activity and cardiometabolic risk markers. Methods: A cross-sectional study using the International Children’s Accelerometry Database (ICAD) including 38,306 observations (in 29,734 individuals aged 4–18 years). Accelerometry data was summarized as time accumulated in 16 combinations of intensity thresholds (≥500 to ≥3000 counts/min) and bout-durations (≥1 to ≥10 min). Outcomes were body mass index (BMI, kg/m2), waist circumference, biochemical markers, blood pressure, and a composite score of these metabolic markers. A second composite score excluded the adiposity component. Linear mixed models were applied to elucidate the associations and expressed per 10 min difference in daily activity above the intensity/bout-duration combination. Estimates (and variance) from each of the 16 combinations of intensity and bout-duration examined in the linear mixed models were analyzed in meta-regression to investigate trends in the association. Results: Each 10 min positive difference in physical activity was significantly and inversely associated with the risk factors irrespective of the combination of intensity and bout-duration. In meta-regression, each 1000 counts/min increase in intensity threshold was associated with a −0.027 (95% CI: −0.039 to −0.014) standard deviations lower composite risk score, and a −0.064 (95% CI: −0.09 to −0.038) kg/m2 lower BMI. Conversely, meta-regression suggested bout-duration was not significantly associated with effect-sizes (per 1 min increase in bout-duration: −0.002 (95% CI: −0.005 to 0.0005) standard deviations for the composite risk score, and −0.005 (95% CI: −0.012 to 0.002) kg/m2 for BMI). Conclusions: Time spent at higher intensity physical activity was the main determinant of variation in cardiometabolic risk factors, not bout-duration. Greater magnitude of associations was consistently observed with higher intensities. These results suggest that, in children and adolescents, physical activity, preferably at higher intensities, of any bout-duration should be promoted.

UR - http://www.scopus.com/inward/record.url?scp=85049851563&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/physical-activity-intensity-boutduration-cardiometabolic-risk-markers-children-adolescents

U2 - 10.1038/s41366-018-0152-8

DO - 10.1038/s41366-018-0152-8

M3 - Article

VL - 42

SP - 1639

EP - 1650

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 9

ER -