TY - JOUR
T1 - Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis
T2 - Is exercise the cause?
AU - Whyte, G.
AU - Sheppard, M.
AU - George, K.
AU - Shave, R.
AU - Wilson, M.
AU - Prasad, S.
AU - O'Hanlon, R.
AU - Sharma, S.
PY - 2008/4
Y1 - 2008/4
N2 - A growing body of evidence reporting altered cardiac function and myocardial damage after arduous exercise, together with the increased prevalence of arrhythmias observed in highly trained athletes, suggests that repetitive bouts of prolonged, arduous exercise may be deleterious to long-term cardiac health. We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.
AB - A growing body of evidence reporting altered cardiac function and myocardial damage after arduous exercise, together with the increased prevalence of arrhythmias observed in highly trained athletes, suggests that repetitive bouts of prolonged, arduous exercise may be deleterious to long-term cardiac health. We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.
UR - http://www.scopus.com/inward/record.url?scp=39849098409&partnerID=8YFLogxK
U2 - 10.1136/bjsm.2007.038158
DO - 10.1136/bjsm.2007.038158
M3 - Comment/debate
C2 - 17720799
AN - SCOPUS:39849098409
SN - 0306-3674
VL - 42
SP - 304
EP - 305
JO - British Journal of Sports Medicine
JF - British Journal of Sports Medicine
IS - 4
ER -