Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil

J Thomas, C Narkowicz, G M Peterson, G A Jacobson, A Narayana

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The efficacy of an ointment containing kunzea oil for the treatment of horses with localised acute or chronic pastern dermatitis was assessed. Thirty-seven horses were randomly allocated to treatment with an ointment containing either 20 per cent kunzea oil (test) or 2 per cent ketoconazole (control). Only 21 of the horses completed the study. The severity of the lesions was assessed before and after seven days of treatment. The kunzea oil formulation resulted in a significant decrease in the median total area of the lesions from 40 cm(2) (range 3 to 252 cm(2)) to 0 cm(2) (range 0 to 34 cm(2)), with complete resolution of the signs of pastern dermatitis in seven of 11 cases. The control formulation resulted in no significant change in the total area of the lesions, and the signs of pastern dermatitis resolved completely in only two of the 10 cases.

Original languageEnglish
Pages (from-to)619-623
Number of pages5
JournalVeterinary Record
Volume164
Issue number20
DOIs
Publication statusPublished - 16 May 2009
Externally publishedYes

Fingerprint

Kunzea
Dermatitis
dermatitis
Horses
ointments
Oils
Randomized Controlled Trials
Ointments
horses
oils
ketoconazole
Ketoconazole
testing

Cite this

Thomas, J ; Narkowicz, C ; Peterson, G M ; Jacobson, G A ; Narayana, A. / Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil. In: Veterinary Record. 2009 ; Vol. 164, No. 20. pp. 619-623.
@article{ea74b1b934a2494ca76341eafc52687c,
title = "Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil",
abstract = "The efficacy of an ointment containing kunzea oil for the treatment of horses with localised acute or chronic pastern dermatitis was assessed. Thirty-seven horses were randomly allocated to treatment with an ointment containing either 20 per cent kunzea oil (test) or 2 per cent ketoconazole (control). Only 21 of the horses completed the study. The severity of the lesions was assessed before and after seven days of treatment. The kunzea oil formulation resulted in a significant decrease in the median total area of the lesions from 40 cm(2) (range 3 to 252 cm(2)) to 0 cm(2) (range 0 to 34 cm(2)), with complete resolution of the signs of pastern dermatitis in seven of 11 cases. The control formulation resulted in no significant change in the total area of the lesions, and the signs of pastern dermatitis resolved completely in only two of the 10 cases.",
keywords = "Animals, Antifungal Agents, Dermatitis, Female, Hindlimb, Horse Diseases, Horses, Ketoconazole, Kunzea, Male, Ointments, Phytotherapy, Plant Oils, Statistics, Nonparametric, Treatment Outcome, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",
author = "J Thomas and C Narkowicz and Peterson, {G M} and Jacobson, {G A} and A Narayana",
year = "2009",
month = "5",
day = "16",
doi = "10.1136/vr.164.20.619",
language = "English",
volume = "164",
pages = "619--623",
journal = "Veterinary Record",
issn = "0042-4900",
publisher = "British Veterinary Association",
number = "20",

}

Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil. / Thomas, J; Narkowicz, C; Peterson, G M; Jacobson, G A; Narayana, A.

In: Veterinary Record, Vol. 164, No. 20, 16.05.2009, p. 619-623.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil

AU - Thomas, J

AU - Narkowicz, C

AU - Peterson, G M

AU - Jacobson, G A

AU - Narayana, A

PY - 2009/5/16

Y1 - 2009/5/16

N2 - The efficacy of an ointment containing kunzea oil for the treatment of horses with localised acute or chronic pastern dermatitis was assessed. Thirty-seven horses were randomly allocated to treatment with an ointment containing either 20 per cent kunzea oil (test) or 2 per cent ketoconazole (control). Only 21 of the horses completed the study. The severity of the lesions was assessed before and after seven days of treatment. The kunzea oil formulation resulted in a significant decrease in the median total area of the lesions from 40 cm(2) (range 3 to 252 cm(2)) to 0 cm(2) (range 0 to 34 cm(2)), with complete resolution of the signs of pastern dermatitis in seven of 11 cases. The control formulation resulted in no significant change in the total area of the lesions, and the signs of pastern dermatitis resolved completely in only two of the 10 cases.

AB - The efficacy of an ointment containing kunzea oil for the treatment of horses with localised acute or chronic pastern dermatitis was assessed. Thirty-seven horses were randomly allocated to treatment with an ointment containing either 20 per cent kunzea oil (test) or 2 per cent ketoconazole (control). Only 21 of the horses completed the study. The severity of the lesions was assessed before and after seven days of treatment. The kunzea oil formulation resulted in a significant decrease in the median total area of the lesions from 40 cm(2) (range 3 to 252 cm(2)) to 0 cm(2) (range 0 to 34 cm(2)), with complete resolution of the signs of pastern dermatitis in seven of 11 cases. The control formulation resulted in no significant change in the total area of the lesions, and the signs of pastern dermatitis resolved completely in only two of the 10 cases.

KW - Animals

KW - Antifungal Agents

KW - Dermatitis

KW - Female

KW - Hindlimb

KW - Horse Diseases

KW - Horses

KW - Ketoconazole

KW - Kunzea

KW - Male

KW - Ointments

KW - Phytotherapy

KW - Plant Oils

KW - Statistics, Nonparametric

KW - Treatment Outcome

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1136/vr.164.20.619

DO - 10.1136/vr.164.20.619

M3 - Article

VL - 164

SP - 619

EP - 623

JO - Veterinary Record

JF - Veterinary Record

SN - 0042-4900

IS - 20

ER -