Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 132-134 |
| Number of pages | 3 |
| Journal | Cytogenetics and Cell Genetics |
| Volume | 116 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 2007 |
| Externally published | Yes |
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Reassignment of chicken W chromosome sequences to the Z chromosome by fluorescence in situ hybridization (FISH). / Stiglec, Rami; Ezaz, Tariq; Graves, Jenny.
In: Cytogenetics and Cell Genetics, Vol. 116, No. 1-2, 2007, p. 132-134.Research output: Contribution to journal › Article
TY - JOUR
T1 - Reassignment of chicken W chromosome sequences to the Z chromosome by fluorescence in situ hybridization (FISH)
AU - Stiglec, Rami
AU - Ezaz, Tariq
AU - Graves, Jenny
N1 - cited By 13
PY - 2007
Y1 - 2007
N2 - There is much interest in the gene content of the small heterochromatic W chromosome of the chicken, on the supposition that it may contain sex-determining genes. A considerable region in the chicken genome has been assigned to the W chromosome on the basis of its repetitive sequences. Using fluorescent in situ hybridization (FISH) we localized five Bacterial Artificial Chromosomes (BACs) onto female chicken metaphase spreads. We physically mapped these BACs to the Z chromosome. The chicken genome database, however, assigned all five BACs to the W chromosome. Our results demonstrate that the 17 genes on these BACs are Z-specific, and points to the inadequacy of assigning regions of the genome based exclusively on repetitive sequences
AB - There is much interest in the gene content of the small heterochromatic W chromosome of the chicken, on the supposition that it may contain sex-determining genes. A considerable region in the chicken genome has been assigned to the W chromosome on the basis of its repetitive sequences. Using fluorescent in situ hybridization (FISH) we localized five Bacterial Artificial Chromosomes (BACs) onto female chicken metaphase spreads. We physically mapped these BACs to the Z chromosome. The chicken genome database, however, assigned all five BACs to the W chromosome. Our results demonstrate that the 17 genes on these BACs are Z-specific, and points to the inadequacy of assigning regions of the genome based exclusively on repetitive sequences
U2 - 10.1159/000097432
DO - 10.1159/000097432
M3 - Article
VL - 116
SP - 132
EP - 134
JO - Cytogenetics and Cell Genetics
JF - Cytogenetics and Cell Genetics
SN - 0301-0171
IS - 1-2
ER -