Nitre goosefoot (Chenopodium nitrariaceum (F.Muell.) is a woody shrub that occurs at the edges of floodplains and other intermittently flooded areas across the Murray-Darling Basin. No studies have been conducted on the hydrological requirements of nitre goosefoot, and the species is not considered in watering requirements of floodplain species of the Murray-Darling Basin. This study investigated the effects of simulated rainfall and depth and duration of experimental flooding on mortality, leaf production, biomass and seed production of nitre goosefoot. Nitre goosefoot plants were grown from seeds collected near Hillston, New South Wales, Australia. The plants were subjected to the following 14 hydrological treatments: dry (no water applied), rainfall (simulating rainfall conditions at Hillston) and 12 combinations of three water depths (10 cm, 50 cm, 75 cm) with four durations of inundation (5 days, 10 days, 20 days, 40 days). The study found that nitre goosefoot plants survived flooding, providing plants were not totally submerged, leaf production increased during flooding and after drawdown, and leaf production, biomass and seeding were highest under shallow flooding for approximately 1 month. The results of the study allow the hydrological requirements of nitre goosefoot to be considered in environmental watering programs.