SARS-CoV-2/COVID-19: Salient Facts and Strategies to Combat Ongoing Pandemic

Ranjit Sah, Nayanum Pokhrel, Zareena Fathah, Akihiko Ozaki, Divya Bhandari, Yasuhiro Kotera, Niranjan Prasad Shah, Shailendra Sigdel, Kranti Suresh Vora, Senthil Kumar Natesan, Shailesh Kumar Patel, Ruchi Tiwari, Yashpal Singh Malik, Mohd Iqbal Yatoo, Alfonso J. Rodriguez-Morales, Kuldeep Dhama

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2), an emerging novel coronavirus causing coronavirus disease 2019 (COVID-19) pandemic, has now rapidly spread to more than 215 countries and has killed nearly 0.75 million people out of more than 20 million confirmed cases as of 10th August, 2020. Apart from affecting respiratory system, the virus has shown multiple manifestations with neurological affections and damaging kidneys. SARS-CoV-2 transmission mainly occurs through close contact of COVID-19 affected person, however air-borne route is also now considered as dominant route of virus spread. The virus has been implicated to have originated from animals. Apart from bats, pangolins and others being investigates to play role in transmitting SARS-CoV-2 as intermediate hosts, the recent reports of this virus infection in other animals (cats, dogs, tigers, lions, mink) suggest one health approach implementation along with adopting appropriate mitigation strategies. Researchers are pacing to develop effective vaccines and drugs, few reached to clinical trials also, however these may take time to reach the mass population, and so till then adopting appropriate prevention and control is the best option to avoid SARS-CoV-2 infection. This article presents an overview on this pandemic virus and the disease it causes, with few recent concepts and advances.
Original languageEnglish
Pages (from-to)1663-1674
Number of pages12
JournalJournal of Pure and Applied Microbiology
Volume14
Issue number3
DOIs
Publication statusPublished - Sep 2020

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