Searching for the biological pathways between stress and health

Shona Kelly, Clyde Hertzman, Mark Daniels

Research output: Contribution to journalReview article

88 Citations (Scopus)

Abstract

Population-based, person-specific health surveys, with concomitant biological measures, should provide important information about the processes by which socioeconomic and psychosocial factors embed themselves in human health. Questionnaire responses allow for assessment of the perceived psychosocial environment, but biological measurements will measure the status of the psychoneuroimmunology/psychoneuroendocrinology (PNI/PNE) pathways and may allow us to identify people who have 'adapted' to their stress because of experience, expectations, stoicism, etc. This review sets criteria to evaluate potential physiological markers of chronic stress. Because population health surveys involve a massive number of samples, special consideration must be given to the laboratory analysis method and transportation time of the markers chosen. We reviewed five areas: glycosylated proteins, the immune system, hemostasis, peripheral benzodiazepine receptors, and the waist-hip ratio.

Original languageEnglish
Pages (from-to)437-462
Number of pages26
JournalAnnual Review of Public Health
Volume18
DOIs
Publication statusPublished - May 1997
Externally publishedYes

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Health Surveys
Psychoneuroimmunology
Waist-Hip Ratio
Health
GABA-A Receptors
Hemostasis
Population
Immune System
Psychology
Proteins
Surveys and Questionnaires

Cite this

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Searching for the biological pathways between stress and health. / Kelly, Shona; Hertzman, Clyde; Daniels, Mark.

In: Annual Review of Public Health, Vol. 18, 05.1997, p. 437-462.

Research output: Contribution to journalReview article

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