Serodiagnosis of toxaplasmosis in a common wombat

L.F. Skerrat, J Phelan, Rosemary McFarlane, R Speare

Research output: Contribution to journalArticle

Abstract

An 8-yr-old captive, female common wombat (Vombatus ursinus) from Victoria, Australia was euthanased after an illness of 36 days manifested by lethargy, inappetance and terminal coma with respiratory failure. Toxoplasmosis was diagnosed during life by the Toxoplasma direct agglutination test (DAT) which showed a positive initial titre of 1:1,024 at 22 days after onset of illness and a four fold rise in titre to 1:4,098 2 wk later, just prior to death. The Toxoplasma modified agglutination test (MAT) remained negative over this time period. The serological diagnosis was confirmed by histological diagnosis of granulomatous encephalitis, focal myocarditis, interstitial pneumonia and severe adrenal cortical necrosis and the presence of tachyzoites of Toxoplasma gondii in large numbers within the focal necrotic lesions in the brain, myocardium and adrenal cortices. The serological response in the wombat differed from that of the typical eutherian which exhibits a reaction in both the DAT and MAT within 2 wk of infection with T. gondii. An incidental finding was calcification in the media of the ascending aorta and proximal parts of the major arteries.
Original languageEnglish
Pages (from-to)346-351
Number of pages6
JournalJournal of Wildlife Diseases
Volume33
Issue number2
DOIs
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Agglutination Tests
serodiagnosis
agglutination tests
Serologic Tests
Toxoplasma
Toxoplasmosis
Toxoplasma gondii
Victoria (Australia)
encephalitis
coma
myocarditis
adrenal cortex
Lethargy
tachyzoites
Sick Leave
Incidental Findings
pneumonia
Victoria
toxoplasmosis
Adrenal Cortex

Cite this

Skerrat, L.F. ; Phelan, J ; McFarlane, Rosemary ; Speare, R. / Serodiagnosis of toxaplasmosis in a common wombat. In: Journal of Wildlife Diseases. 1997 ; Vol. 33, No. 2. pp. 346-351.
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Serodiagnosis of toxaplasmosis in a common wombat. / Skerrat, L.F.; Phelan, J; McFarlane, Rosemary; Speare, R.

In: Journal of Wildlife Diseases, Vol. 33, No. 2, 1997, p. 346-351.

Research output: Contribution to journalArticle

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T1 - Serodiagnosis of toxaplasmosis in a common wombat

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