Sex and racial/ethnic differences in premature mortality due to HIV: Florida, 2000–2009

Mary Trepka, Theo NIYONSENGA, Kristopher Fennie, Karma McKelvey, Spencer Lieb, Lorene Maddox

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective. This study aimed to characterize premature mortality among people diagnosed with HIV infection from 2000 to 2009 in Florida, by sex and race/ ethnicity, to estimate differences in premature mortality that could be prevented by linkage to HIV care and treatment. Methods. Florida surveillance data for HIV diagnoses (excluding concurrent AIDS diagnoses) were linked with vital records data to ascertain deaths through 2011. Years of potential life lost (YPLL) were obtained from the expected number of remaining years of life at a given age from the U.S. sex-specific period life tables. Results. Among 41,565 people diagnosed with HIV infection during the study period, 5,249 died, and 2,563 (48.8%) deaths were due to HIV/AIDS. Age-standardized YPLL (aYPLL) due to HIV/AIDS per 1,000 person-years was significantly higher for females than males (372.6, 95% confidence interval [CI] 349.8, 396.2 vs. 295.2, 95% CI 278.4, 312.5); for non-Hispanic black (NHB) females than non-Hispanic white (NHW) and Hispanic females (388.2, 95% CI 360.7, 416.9; 294.3, 95% CI 239.8, 354.9; and 295.0, 95% CI 242.9, 352.5, respectively); and for NHB males compared with NHW and Hispanic males (378.7, 95% CI 353.7, 404.7; 210.6, 95% CI 174.3, 250.8; and 240.9, 95% CI 204.8, 280.2, respectively). In multilevel modeling controlling for individual factors, NHB race was associated with YPLL due to HIV/AIDS for women (p50.04) and men (p<0.001). Conclusion. Among people diagnosed with HIV infection, females and NHB people had a disproportionately high premature mortality from HIV/AIDS, suggesting the need for enhanced efforts to improve linkage to and retention in care and medication adherence for these groups.

Original languageEnglish
Pages (from-to)505-513
Number of pages9
JournalPublic Health Reports
Volume130
Issue number5
DOIs
Publication statusPublished - 1 Sep 2015
Externally publishedYes

Fingerprint

Premature Mortality
HIV
Confidence Intervals
Acquired Immunodeficiency Syndrome
Life Expectancy
HIV Infections
Hispanic Americans
Life Tables
Medication Adherence

Cite this

Trepka, Mary ; NIYONSENGA, Theo ; Fennie, Kristopher ; McKelvey, Karma ; Lieb, Spencer ; Maddox, Lorene. / Sex and racial/ethnic differences in premature mortality due to HIV: Florida, 2000–2009. In: Public Health Reports. 2015 ; Vol. 130, No. 5. pp. 505-513.
@article{0a1d4bdb992c491ab79f18f0bd085d22,
title = "Sex and racial/ethnic differences in premature mortality due to HIV: Florida, 2000–2009",
abstract = "Objective. This study aimed to characterize premature mortality among people diagnosed with HIV infection from 2000 to 2009 in Florida, by sex and race/ ethnicity, to estimate differences in premature mortality that could be prevented by linkage to HIV care and treatment. Methods. Florida surveillance data for HIV diagnoses (excluding concurrent AIDS diagnoses) were linked with vital records data to ascertain deaths through 2011. Years of potential life lost (YPLL) were obtained from the expected number of remaining years of life at a given age from the U.S. sex-specific period life tables. Results. Among 41,565 people diagnosed with HIV infection during the study period, 5,249 died, and 2,563 (48.8{\%}) deaths were due to HIV/AIDS. Age-standardized YPLL (aYPLL) due to HIV/AIDS per 1,000 person-years was significantly higher for females than males (372.6, 95{\%} confidence interval [CI] 349.8, 396.2 vs. 295.2, 95{\%} CI 278.4, 312.5); for non-Hispanic black (NHB) females than non-Hispanic white (NHW) and Hispanic females (388.2, 95{\%} CI 360.7, 416.9; 294.3, 95{\%} CI 239.8, 354.9; and 295.0, 95{\%} CI 242.9, 352.5, respectively); and for NHB males compared with NHW and Hispanic males (378.7, 95{\%} CI 353.7, 404.7; 210.6, 95{\%} CI 174.3, 250.8; and 240.9, 95{\%} CI 204.8, 280.2, respectively). In multilevel modeling controlling for individual factors, NHB race was associated with YPLL due to HIV/AIDS for women (p50.04) and men (p<0.001). Conclusion. Among people diagnosed with HIV infection, females and NHB people had a disproportionately high premature mortality from HIV/AIDS, suggesting the need for enhanced efforts to improve linkage to and retention in care and medication adherence for these groups.",
keywords = "Adult, African Americans/statistics & numerical data, Antiretroviral Therapy, Highly Active/statistics & numerical data, Cause of Death, Early Diagnosis, European Continental Ancestry Group/statistics & numerical data, Female, Florida/epidemiology, HIV Infections/diagnosis, Healthcare Disparities/economics, Hispanic Americans/statistics & numerical data, Humans, Male, Middle Aged, Minority Health/economics, Mortality, Premature/ethnology, Multilevel Analysis, Population Surveillance, Poverty Areas, Sex Distribution, Young Adult",
author = "Mary Trepka and Theo NIYONSENGA and Kristopher Fennie and Karma McKelvey and Spencer Lieb and Lorene Maddox",
year = "2015",
month = "9",
day = "1",
doi = "10.1177/003335491513000513",
language = "English",
volume = "130",
pages = "505--513",
journal = "Health services reports",
issn = "0033-3549",
publisher = "Association of Schools of Public Health",
number = "5",

}

Sex and racial/ethnic differences in premature mortality due to HIV: Florida, 2000–2009. / Trepka, Mary; NIYONSENGA, Theo; Fennie, Kristopher; McKelvey, Karma; Lieb, Spencer; Maddox, Lorene.

In: Public Health Reports, Vol. 130, No. 5, 01.09.2015, p. 505-513.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Sex and racial/ethnic differences in premature mortality due to HIV: Florida, 2000–2009

AU - Trepka, Mary

AU - NIYONSENGA, Theo

AU - Fennie, Kristopher

AU - McKelvey, Karma

AU - Lieb, Spencer

AU - Maddox, Lorene

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Objective. This study aimed to characterize premature mortality among people diagnosed with HIV infection from 2000 to 2009 in Florida, by sex and race/ ethnicity, to estimate differences in premature mortality that could be prevented by linkage to HIV care and treatment. Methods. Florida surveillance data for HIV diagnoses (excluding concurrent AIDS diagnoses) were linked with vital records data to ascertain deaths through 2011. Years of potential life lost (YPLL) were obtained from the expected number of remaining years of life at a given age from the U.S. sex-specific period life tables. Results. Among 41,565 people diagnosed with HIV infection during the study period, 5,249 died, and 2,563 (48.8%) deaths were due to HIV/AIDS. Age-standardized YPLL (aYPLL) due to HIV/AIDS per 1,000 person-years was significantly higher for females than males (372.6, 95% confidence interval [CI] 349.8, 396.2 vs. 295.2, 95% CI 278.4, 312.5); for non-Hispanic black (NHB) females than non-Hispanic white (NHW) and Hispanic females (388.2, 95% CI 360.7, 416.9; 294.3, 95% CI 239.8, 354.9; and 295.0, 95% CI 242.9, 352.5, respectively); and for NHB males compared with NHW and Hispanic males (378.7, 95% CI 353.7, 404.7; 210.6, 95% CI 174.3, 250.8; and 240.9, 95% CI 204.8, 280.2, respectively). In multilevel modeling controlling for individual factors, NHB race was associated with YPLL due to HIV/AIDS for women (p50.04) and men (p<0.001). Conclusion. Among people diagnosed with HIV infection, females and NHB people had a disproportionately high premature mortality from HIV/AIDS, suggesting the need for enhanced efforts to improve linkage to and retention in care and medication adherence for these groups.

AB - Objective. This study aimed to characterize premature mortality among people diagnosed with HIV infection from 2000 to 2009 in Florida, by sex and race/ ethnicity, to estimate differences in premature mortality that could be prevented by linkage to HIV care and treatment. Methods. Florida surveillance data for HIV diagnoses (excluding concurrent AIDS diagnoses) were linked with vital records data to ascertain deaths through 2011. Years of potential life lost (YPLL) were obtained from the expected number of remaining years of life at a given age from the U.S. sex-specific period life tables. Results. Among 41,565 people diagnosed with HIV infection during the study period, 5,249 died, and 2,563 (48.8%) deaths were due to HIV/AIDS. Age-standardized YPLL (aYPLL) due to HIV/AIDS per 1,000 person-years was significantly higher for females than males (372.6, 95% confidence interval [CI] 349.8, 396.2 vs. 295.2, 95% CI 278.4, 312.5); for non-Hispanic black (NHB) females than non-Hispanic white (NHW) and Hispanic females (388.2, 95% CI 360.7, 416.9; 294.3, 95% CI 239.8, 354.9; and 295.0, 95% CI 242.9, 352.5, respectively); and for NHB males compared with NHW and Hispanic males (378.7, 95% CI 353.7, 404.7; 210.6, 95% CI 174.3, 250.8; and 240.9, 95% CI 204.8, 280.2, respectively). In multilevel modeling controlling for individual factors, NHB race was associated with YPLL due to HIV/AIDS for women (p50.04) and men (p<0.001). Conclusion. Among people diagnosed with HIV infection, females and NHB people had a disproportionately high premature mortality from HIV/AIDS, suggesting the need for enhanced efforts to improve linkage to and retention in care and medication adherence for these groups.

KW - Adult

KW - African Americans/statistics & numerical data

KW - Antiretroviral Therapy, Highly Active/statistics & numerical data

KW - Cause of Death

KW - Early Diagnosis

KW - European Continental Ancestry Group/statistics & numerical data

KW - Female

KW - Florida/epidemiology

KW - HIV Infections/diagnosis

KW - Healthcare Disparities/economics

KW - Hispanic Americans/statistics & numerical data

KW - Humans

KW - Male

KW - Middle Aged

KW - Minority Health/economics

KW - Mortality, Premature/ethnology

KW - Multilevel Analysis

KW - Population Surveillance

KW - Poverty Areas

KW - Sex Distribution

KW - Young Adult

UR - http://www.scopus.com/inward/record.url?scp=84940373901&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/sex-racialethnic-differences-premature-mortality-due-hiv-florida-20002009

U2 - 10.1177/003335491513000513

DO - 10.1177/003335491513000513

M3 - Article

VL - 130

SP - 505

EP - 513

JO - Health services reports

JF - Health services reports

SN - 0033-3549

IS - 5

ER -