Statin therapy, myopathy and exercise - A case report

Research output: Contribution to journalArticle

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Abstract

In a bid to reduce the morbidity and mortality associated with coronary artery disease, statin therapy has become a cornerstone treatment for patients with dyslipideamia. Statins, or HMG-CoA reductase inhibitors, are effective in blocking hepatic synthesis of cholesterol and are generally regarded as safe. Although rare, severe adverse side effects such as rhabdomyolysis have been reported, however, the more common complaint from patients is that related to myopathy.
Original languageEnglish
Pages (from-to)40-41
Number of pages2
JournalLipids in Health and Disease
Volume11
DOIs
Publication statusPublished - 2012
Externally publishedYes

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Exercise Therapy
Muscular Diseases
Rhabdomyolysis
Coronary Artery Disease
Cholesterol
Morbidity
Mortality
Liver
Therapeutics

Cite this

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title = "Statin therapy, myopathy and exercise - A case report",
abstract = "In a bid to reduce the morbidity and mortality associated with coronary artery disease, statin therapy has become a cornerstone treatment for patients with dyslipideamia. Statins, or HMG-CoA reductase inhibitors, are effective in blocking hepatic synthesis of cholesterol and are generally regarded as safe. Although rare, severe adverse side effects such as rhabdomyolysis have been reported, however, the more common complaint from patients is that related to myopathy.",
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Statin therapy, myopathy and exercise - A case report. / SEMPLE, Stuart.

In: Lipids in Health and Disease, Vol. 11, 2012, p. 40-41.

Research output: Contribution to journalArticle

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AU - SEMPLE, Stuart

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N2 - In a bid to reduce the morbidity and mortality associated with coronary artery disease, statin therapy has become a cornerstone treatment for patients with dyslipideamia. Statins, or HMG-CoA reductase inhibitors, are effective in blocking hepatic synthesis of cholesterol and are generally regarded as safe. Although rare, severe adverse side effects such as rhabdomyolysis have been reported, however, the more common complaint from patients is that related to myopathy.

AB - In a bid to reduce the morbidity and mortality associated with coronary artery disease, statin therapy has become a cornerstone treatment for patients with dyslipideamia. Statins, or HMG-CoA reductase inhibitors, are effective in blocking hepatic synthesis of cholesterol and are generally regarded as safe. Although rare, severe adverse side effects such as rhabdomyolysis have been reported, however, the more common complaint from patients is that related to myopathy.

KW - Exercise

KW - Inflammation

KW - Lipids

KW - Simvastatin

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M3 - Article

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JF - Lipids in Health and Disease

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