Strict glycemic control and mortality risk among US adults with type 2 diabetes

Evelyn Davila; Hermes Florez; Mary Trepka; Lora Fleming; Theo NIYONSENGA; David J. Lee; Jai Parkash

doi:10.1016/j.jdiacomp.2011.03.004

Strict glycemic control and mortality risk among US adults with type 2 diabetes

Evelyn Davila
, Hermes Florez
, Mary Trepka
, Lora Fleming
, Theo NIYONSENGA
, David J. Lee
, Jai Parkash

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Objective
To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity.

Methods
Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988–1994) and its linked mortality file (with follow-up death up to 2000) were used.

Results
Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48–0.98). However, among those with strict glycemic control levels, statistically significant results were not found.

Conclusion
Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

Original language	English
Pages (from-to)	289-291
Number of pages	3
Journal	Journal of Diabetes and Its Complications
Volume	25
Issue number	5
DOIs	https://doi.org/10.1016/j.jdiacomp.2011.03.004
Publication status	Published - 2011
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.jdiacomp.2011.03.004

Cite this

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title = "Strict glycemic control and mortality risk among US adults with type 2 diabetes",

abstract = "Objective To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988–1994) and its linked mortality file (with follow-up death up to 2000) were used. Results Having strict glycemic control (i.e., HbA1c ≤6.5\%) was associated with a lower risk of mortality (hazards ratio=0.69; 95\% confidence interval=0.48–0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups. ",

author = "Evelyn Davila and Hermes Florez and Mary Trepka and Lora Fleming and Theo NIYONSENGA and Lee, \{David J.\} and Jai Parkash",

year = "2011",

doi = "10.1016/j.jdiacomp.2011.03.004",

language = "English",

volume = "25",

pages = "289--291",

journal = "Journal of Diabetes and Its Complications",

issn = "1056-8727",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Strict glycemic control and mortality risk among US adults with type 2 diabetes

AU - Davila, Evelyn

AU - Florez, Hermes

AU - Trepka, Mary

AU - Fleming, Lora

AU - NIYONSENGA, Theo

AU - Lee, David J.

AU - Parkash, Jai

PY - 2011

Y1 - 2011

N2 - Objective To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988–1994) and its linked mortality file (with follow-up death up to 2000) were used. Results Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48–0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

AB - Objective To assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity. Methods Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988–1994) and its linked mortality file (with follow-up death up to 2000) were used. Results Having strict glycemic control (i.e., HbA1c ≤6.5%) was associated with a lower risk of mortality (hazards ratio=0.69; 95% confidence interval=0.48–0.98). However, among those with strict glycemic control levels, statistically significant results were not found. Conclusion Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.

U2 - 10.1016/j.jdiacomp.2011.03.004

DO - 10.1016/j.jdiacomp.2011.03.004

M3 - Article

SN - 1056-8727

VL - 25

SP - 289

EP - 291

JO - Journal of Diabetes and Its Complications

JF - Journal of Diabetes and Its Complications

IS - 5

ER -

Strict glycemic control and mortality risk among US adults with type 2 diabetes

Abstract

UN SDGs

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