Sub-2 μm Silica Particles in Chiral Separation

Diana  IBRAHIM; Ashraf GHANEM

doi:10.5772/intechopen.79063

Sub-2 μm Silica Particles in Chiral Separation

Diana IBRAHIM, Ashraf GHANEM

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Abstract

For decades, the race for the shortest chromatogram with the best resolution and separation efficiency has been the focus of researchers and manufacturers. Considerable advancement has been attained in the field of separation science with the widespread application and outstanding performance in nanomaterials. According to the van Deemter equation, sub-2 micron particles employed in conventional HPLC short column should subsequently result in analysis time reduction and efficiency improvements without the drawback of high pressure associated with sub-2 micron particles. This chapter provides comprehensive discussion about the applications of the new sub 2 microns silica particles in chiral separation of racemates.

Original language	English
Title of host publication	New Uses of Micro and Nanomaterials
Editors	Marcelo Ruben Pagnola, Jairo Useche Vivero, Andres Guillermo Marrugo
Place of Publication	Hungary
Publisher	IntechOpen
Chapter	4
Pages	55-72
Number of pages	18
ISBN (Print)	9781789841749, 9781789841732
DOIs	https://doi.org/10.5772/intechopen.79063
Publication status	Published - 10 Oct 2018

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AB - For decades, the race for the shortest chromatogram with the best resolution and separation efficiency has been the focus of researchers and manufacturers. Considerable advancement has been attained in the field of separation science with the widespread application and outstanding performance in nanomaterials. According to the van Deemter equation, sub-2 micron particles employed in conventional HPLC short column should subsequently result in analysis time reduction and efficiency improvements without the drawback of high pressure associated with sub-2 micron particles. This chapter provides comprehensive discussion about the applications of the new sub 2 microns silica particles in chiral separation of racemates.

KW - CHIRALPAK IG-U

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KW - Chrial separation

KW - sub-2 micron

KW - nanomaterials

UR - https://www.intechopen.com/books/new-uses-of-micro-and-nanomaterials/sub-2-m-silica-particles-in-chiral-separation

UR - http://www.mendeley.com/research/sub2-%CE%BCm-silica-particles-chiral-separation

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DO - 10.5772/intechopen.79063

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BT - New Uses of Micro and Nanomaterials

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A2 - Vivero, Jairo Useche

A2 - Marrugo, Andres Guillermo

PB - IntechOpen

CY - Hungary

ER -

Sub-2 μm Silica Particles in Chiral Separation

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