Systematic review of clinical practice guidelines to identify recommendations for sleep in type 2 diabetes mellitus management

Aisling Smyth, Mark Jenkins, Melissa Dunham, Yvonne Kutzer, Shahrad Taheri, Lisa Whitehead

Research output: Contribution to journalReview articlepeer-review


INTRODUCTION: Sleep quality, quantity and timing have been shown to impact glycaemic control, with a role in insulin sensitivity, glucose tolerance and HbA1C levels, in both diabetic and non-diabetic populations. The aim of this study was to identify recommendations for sleep assessment and management in international clinical practice guidelines focused on type 2 diabetes mellitus management in adults.

STUDY DESIGN: Systematic Review.

METHODOLOGY: Clinical practice guidelines which focused on the management of type 2 diabetes mellitus in adults were included (n = 35). Two independent reviewers utilised the Appraisal of Guidelines for Research and Evaluation tool (AGREE) II and a third reviewer resolved any disagreements. Included guidelines were assessed for recommendations about sleep in diabetes management (n = 14). Data were extracted on sleep recommendations ,themes were generated from the extracted data and narrative syntheses were created.

RESULTS: From 1114 identified papers, 35 guidelines met the inclusion criteria. Fourteen of these guidelines included recommendations pertaining to sleep, which broadly fell into five categories; sleep assessment, sleep as a therapeutic target, sleep and co-morbidities of type 2 diabetes mellitus, shift work and sleep and driving. Recommendations varied across guidelines.

CONCLUSION: Few guidelines provided recommendations relating to assessment and management of sleep in type 2 diabetes care. Most of the recommendations were related to obstructive sleep apnoea. However, few guidelines discussed sleep as a therapeutic intervention for diabetes mellitus or described the potential importance of sleep quality and duration in glycaemic control. Prospero registration number: CRD42020142136.

Original languageEnglish
Article number108532
Pages (from-to)1-17
Number of pages17
JournalDiabetes Research and Clinical Practice
Publication statusPublished - Dec 2020
Externally publishedYes


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