The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study

Ekavi N. Georgousopoulou, Nathan M. D'Cunha, Duane D. Mellor, Stefanos Tyrovolas, Nenad Naumovski, Alexandra Foscolou, Vassiliki Bountziouka, Efthimios Gotsis, George Metallinos, Dimitra Tyrovola, Suzanne Piscopo, Giuseppe Valacchi, Nikos Tsakountakis, Akis Zeimbekis, Josep-Antoni Tur, Antonia-Leda Matalas, Evangelos Polychronopoulos, Christos Lionis, Labros Sidossis, Demosthenes B. Panagiotakos

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Metabolic syndrome (MetS) as a combination of features has been known to significantly increase
cardiovascular disease risk, while MetS presence is linked to lifestyle parameters, including physical
activity and dietary habits; recently, the potential impact of sleeping habits has also become an issue under
consideration. The aim of this study was to investigate the role of sleep quantity in several MetS components.
Methods: Design: a cross-sectional observational study. Setting: 26 Mediterranean islands (MEDIS) and the
rural Mani region (Peloponnesus) of Greece. Participants: during 2005–2017, 3130 older (aged 65–100 years)
Mediterranean residents were voluntarily enrolled. Measurements: dietary habits (including MedDietScore
assessment), physical activity status, sociodemographic characteristics, lifestyle parameters (sleeping and
smoking habits), and clinical profile aspects, including MetS components [i.e., waist circumference, systolic and
diastolic blood pressure, fasting glucose, triglycerides, and low-density lipoprotein (LDL) and high-density
lipoprotein cholesterol (HDL-C)], were derived through standard procedures.
Results: The number of daily hours of sleep was independently associated with greater waist circumference [b
coefficient/hr = 0.91, 95% confidence interval (CI): 0.34–1.49], higher LDL-cholesterol levels (b/hr = 3.84, 95%
CI: 0.63–7.05), and lower diastolic blood pressure levels (b/hr=-0.98, 95% CI: -1.57 to -0.39) after adjusting
for participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet,
and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides,
HDL-C, and systolic blood pressure.
Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly individuals, and
further research is needed to identify the paths through which sleep quantity is linked to MetS features in
different age groups.
Original languageEnglish
Pages (from-to)20-28
Number of pages9
JournalMetabolic Syndrome and Related Disorders
Volume16
Issue number1
DOIs
Publication statusPublished - 22 Jan 2018

Cite this

Georgousopoulou, Ekavi N. ; D'Cunha, Nathan M. ; Mellor, Duane D. ; Tyrovolas, Stefanos ; Naumovski, Nenad ; Foscolou, Alexandra ; Bountziouka, Vassiliki ; Gotsis, Efthimios ; Metallinos, George ; Tyrovola, Dimitra ; Piscopo, Suzanne ; Valacchi, Giuseppe ; Tsakountakis, Nikos ; Zeimbekis, Akis ; Tur, Josep-Antoni ; Matalas, Antonia-Leda ; Polychronopoulos, Evangelos ; Lionis, Christos ; Sidossis, Labros ; Panagiotakos, Demosthenes B. / The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study. In: Metabolic Syndrome and Related Disorders. 2018 ; Vol. 16, No. 1. pp. 20-28.
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title = "The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study",
abstract = "Background: Metabolic syndrome (MetS) as a combination of features has been known to significantly increasecardiovascular disease risk, while MetS presence is linked to lifestyle parameters, including physicalactivity and dietary habits; recently, the potential impact of sleeping habits has also become an issue underconsideration. The aim of this study was to investigate the role of sleep quantity in several MetS components.Methods: Design: a cross-sectional observational study. Setting: 26 Mediterranean islands (MEDIS) and therural Mani region (Peloponnesus) of Greece. Participants: during 2005–2017, 3130 older (aged 65–100 years)Mediterranean residents were voluntarily enrolled. Measurements: dietary habits (including MedDietScoreassessment), physical activity status, sociodemographic characteristics, lifestyle parameters (sleeping andsmoking habits), and clinical profile aspects, including MetS components [i.e., waist circumference, systolic anddiastolic blood pressure, fasting glucose, triglycerides, and low-density lipoprotein (LDL) and high-densitylipoprotein cholesterol (HDL-C)], were derived through standard procedures.Results: The number of daily hours of sleep was independently associated with greater waist circumference [bcoefficient/hr = 0.91, 95{\%} confidence interval (CI): 0.34–1.49], higher LDL-cholesterol levels (b/hr = 3.84, 95{\%}CI: 0.63–7.05), and lower diastolic blood pressure levels (b/hr=-0.98, 95{\%} CI: -1.57 to -0.39) after adjustingfor participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet,and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides,HDL-C, and systolic blood pressure.Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly individuals, andfurther research is needed to identify the paths through which sleep quantity is linked to MetS features indifferent age groups.",
keywords = "elderly, lifestyle, MEDIS, Mediterranean-type diet, metabolic syndrome components, sleep",
author = "Georgousopoulou, {Ekavi N.} and D'Cunha, {Nathan M.} and Mellor, {Duane D.} and Stefanos Tyrovolas and Nenad Naumovski and Alexandra Foscolou and Vassiliki Bountziouka and Efthimios Gotsis and George Metallinos and Dimitra Tyrovola and Suzanne Piscopo and Giuseppe Valacchi and Nikos Tsakountakis and Akis Zeimbekis and Josep-Antoni Tur and Antonia-Leda Matalas and Evangelos Polychronopoulos and Christos Lionis and Labros Sidossis and Panagiotakos, {Demosthenes B.}",
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Georgousopoulou, EN, D'Cunha, NM, Mellor, DD, Tyrovolas, S, Naumovski, N, Foscolou, A, Bountziouka, V, Gotsis, E, Metallinos, G, Tyrovola, D, Piscopo, S, Valacchi, G, Tsakountakis, N, Zeimbekis, A, Tur, J-A, Matalas, A-L, Polychronopoulos, E, Lionis, C, Sidossis, L & Panagiotakos, DB 2018, 'The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study', Metabolic Syndrome and Related Disorders, vol. 16, no. 1, pp. 20-28. https://doi.org/10.1089/met.2017.0113

The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study. / Georgousopoulou, Ekavi N.; D'Cunha, Nathan M.; Mellor, Duane D.; Tyrovolas, Stefanos; Naumovski, Nenad; Foscolou, Alexandra; Bountziouka, Vassiliki; Gotsis, Efthimios; Metallinos, George; Tyrovola, Dimitra; Piscopo, Suzanne; Valacchi, Giuseppe; Tsakountakis, Nikos; Zeimbekis, Akis; Tur, Josep-Antoni; Matalas, Antonia-Leda; Polychronopoulos, Evangelos; Lionis, Christos; Sidossis, Labros; Panagiotakos, Demosthenes B.

In: Metabolic Syndrome and Related Disorders, Vol. 16, No. 1, 22.01.2018, p. 20-28.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study

AU - Georgousopoulou, Ekavi N.

AU - D'Cunha, Nathan M.

AU - Mellor, Duane D.

AU - Tyrovolas, Stefanos

AU - Naumovski, Nenad

AU - Foscolou, Alexandra

AU - Bountziouka, Vassiliki

AU - Gotsis, Efthimios

AU - Metallinos, George

AU - Tyrovola, Dimitra

AU - Piscopo, Suzanne

AU - Valacchi, Giuseppe

AU - Tsakountakis, Nikos

AU - Zeimbekis, Akis

AU - Tur, Josep-Antoni

AU - Matalas, Antonia-Leda

AU - Polychronopoulos, Evangelos

AU - Lionis, Christos

AU - Sidossis, Labros

AU - Panagiotakos, Demosthenes B.

PY - 2018/1/22

Y1 - 2018/1/22

N2 - Background: Metabolic syndrome (MetS) as a combination of features has been known to significantly increasecardiovascular disease risk, while MetS presence is linked to lifestyle parameters, including physicalactivity and dietary habits; recently, the potential impact of sleeping habits has also become an issue underconsideration. The aim of this study was to investigate the role of sleep quantity in several MetS components.Methods: Design: a cross-sectional observational study. Setting: 26 Mediterranean islands (MEDIS) and therural Mani region (Peloponnesus) of Greece. Participants: during 2005–2017, 3130 older (aged 65–100 years)Mediterranean residents were voluntarily enrolled. Measurements: dietary habits (including MedDietScoreassessment), physical activity status, sociodemographic characteristics, lifestyle parameters (sleeping andsmoking habits), and clinical profile aspects, including MetS components [i.e., waist circumference, systolic anddiastolic blood pressure, fasting glucose, triglycerides, and low-density lipoprotein (LDL) and high-densitylipoprotein cholesterol (HDL-C)], were derived through standard procedures.Results: The number of daily hours of sleep was independently associated with greater waist circumference [bcoefficient/hr = 0.91, 95% confidence interval (CI): 0.34–1.49], higher LDL-cholesterol levels (b/hr = 3.84, 95%CI: 0.63–7.05), and lower diastolic blood pressure levels (b/hr=-0.98, 95% CI: -1.57 to -0.39) after adjustingfor participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet,and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides,HDL-C, and systolic blood pressure.Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly individuals, andfurther research is needed to identify the paths through which sleep quantity is linked to MetS features indifferent age groups.

AB - Background: Metabolic syndrome (MetS) as a combination of features has been known to significantly increasecardiovascular disease risk, while MetS presence is linked to lifestyle parameters, including physicalactivity and dietary habits; recently, the potential impact of sleeping habits has also become an issue underconsideration. The aim of this study was to investigate the role of sleep quantity in several MetS components.Methods: Design: a cross-sectional observational study. Setting: 26 Mediterranean islands (MEDIS) and therural Mani region (Peloponnesus) of Greece. Participants: during 2005–2017, 3130 older (aged 65–100 years)Mediterranean residents were voluntarily enrolled. Measurements: dietary habits (including MedDietScoreassessment), physical activity status, sociodemographic characteristics, lifestyle parameters (sleeping andsmoking habits), and clinical profile aspects, including MetS components [i.e., waist circumference, systolic anddiastolic blood pressure, fasting glucose, triglycerides, and low-density lipoprotein (LDL) and high-densitylipoprotein cholesterol (HDL-C)], were derived through standard procedures.Results: The number of daily hours of sleep was independently associated with greater waist circumference [bcoefficient/hr = 0.91, 95% confidence interval (CI): 0.34–1.49], higher LDL-cholesterol levels (b/hr = 3.84, 95%CI: 0.63–7.05), and lower diastolic blood pressure levels (b/hr=-0.98, 95% CI: -1.57 to -0.39) after adjustingfor participants’ age, gender, body mass index, daily walking time, level of adherence to Mediterranean diet,and smoking status. No association was revealed between hours of sleep per day and fasting glucose, triglycerides,HDL-C, and systolic blood pressure.Conclusions: Increased hours of sleep is an indicator of metabolic disorders among elderly individuals, andfurther research is needed to identify the paths through which sleep quantity is linked to MetS features indifferent age groups.

KW - elderly

KW - lifestyle

KW - MEDIS

KW - Mediterranean-type diet

KW - metabolic syndrome components

KW - sleep

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UR - http://www.mendeley.com/research/association-between-sleeping-time-metabolic-syndrome-features-among-older-adults-living-mediterranea

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DO - 10.1089/met.2017.0113

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JO - Metabolic Syndrome and Related Disorders

JF - Metabolic Syndrome and Related Disorders

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