The effect of plant extracts on S100B levels in animal pre-clinical trials: a systematic review

Nathan Martin D'CUNHA; Andrew MCKUNE; Ekavi GEORGOUSOPOULOU; Paul D. Roach; Duane MELLOR; Jackson THOMAS; Jane KELLETT; Nenad NAUMOVSKI

doi:10.1016/j.jnim.2017.04.173

The effect of plant extracts on S100B levels in animal pre-clinical trials: a systematic review

Nathan Martin D'CUNHA
, Andrew MCKUNE
, Ekavi GEORGOUSOPOULOU
, Paul D. Roach
, Duane MELLOR
, Jackson THOMAS
, Jane KELLETT
, Nenad NAUMOVSKI

Pharmacy

Research output: Contribution to journal › Meeting Abstract › peer-review

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Abstract

Background/Aims: The calcium binding protein S100B has been associated with significant health effects in humans. Elevated circulating levels in later life cause neuronal apoptosis and brain inflammation, and has been associated with severe and chronic pathology including Alzheimer’s disease. The potential benefits of plant extracts on health have become more widely recognised and investigated. However, to date, their impact on S100B levels are not well defined. The aim of this systematic review was to identify candidate plant extracts and determine their effect on S100B levels in animal pre-clinical trials.

Original language	English
Pages (from-to)	1-1
Number of pages	1
Journal	Journal of Nutrition and Intermediary Metabolism
Volume	8
DOIs	https://doi.org/10.1016/j.jnim.2017.04.173
Publication status	Published - 2017

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AbstractFinal published version, 57.5 KBLicence: CC BY-NC-ND

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title = "The effect of plant extracts on S100B levels in animal pre-clinical trials: a systematic review",

abstract = "Background/Aims: The calcium binding protein S100B has been associated with significant health effects in humans. Elevated circulating levels in later life cause neuronal apoptosis and brain inflammation, and has been associated with severe and chronic pathology including Alzheimer{\textquoteright}s disease. The potential benefits of plant extracts on health have become more widely recognised and investigated. However, to date, their impact on S100B levels are not well defined. The aim of this systematic review was to identify candidate plant extracts and determine their effect on S100B levels in animal pre-clinical trials.",

author = "D'CUNHA, \{Nathan Martin\} and Andrew MCKUNE and Ekavi GEORGOUSOPOULOU and Roach, \{Paul D.\} and Duane MELLOR and Jackson THOMAS and Jane KELLETT and Nenad NAUMOVSKI",

year = "2017",

doi = "10.1016/j.jnim.2017.04.173",

language = "English",

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T1 - The effect of plant extracts on S100B levels in animal pre-clinical trials: a systematic review

AU - D'CUNHA, Nathan Martin

AU - MCKUNE, Andrew

AU - GEORGOUSOPOULOU, Ekavi

AU - Roach, Paul D.

AU - MELLOR, Duane

AU - THOMAS, Jackson

AU - KELLETT, Jane

AU - NAUMOVSKI, Nenad

PY - 2017

Y1 - 2017

N2 - Background/Aims: The calcium binding protein S100B has been associated with significant health effects in humans. Elevated circulating levels in later life cause neuronal apoptosis and brain inflammation, and has been associated with severe and chronic pathology including Alzheimer’s disease. The potential benefits of plant extracts on health have become more widely recognised and investigated. However, to date, their impact on S100B levels are not well defined. The aim of this systematic review was to identify candidate plant extracts and determine their effect on S100B levels in animal pre-clinical trials.

AB - Background/Aims: The calcium binding protein S100B has been associated with significant health effects in humans. Elevated circulating levels in later life cause neuronal apoptosis and brain inflammation, and has been associated with severe and chronic pathology including Alzheimer’s disease. The potential benefits of plant extracts on health have become more widely recognised and investigated. However, to date, their impact on S100B levels are not well defined. The aim of this systematic review was to identify candidate plant extracts and determine their effect on S100B levels in animal pre-clinical trials.

UR - http://www.mendeley.com/research/effect-plant-extracts-s100b-levels-animal-preclinical-trials-systematic-review

U2 - 10.1016/j.jnim.2017.04.173

DO - 10.1016/j.jnim.2017.04.173

M3 - Meeting Abstract

SN - 2352-3859

VL - 8

SP - 1

EP - 1

JO - Journal of Nutrition and Intermediary Metabolism

JF - Journal of Nutrition and Intermediary Metabolism

ER -

The effect of plant extracts on S100B levels in animal pre-clinical trials: a systematic review

Abstract

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