TY - JOUR
T1 - The Epidemiological Profile of Tuberculosis Patients and Risk Factors for Poor Treatment Outcomes in Sarpang District, Bhutan
T2 - A 17 Years Retrospective Study
AU - Rai, Nar Bahadur
AU - Penjor, Kinley
AU - Gurung, Amber Bahadur
AU - Samdrup, Tshewang
AU - Dargay, Yonten
AU - Samzang, Samzang
AU - Wangdi, Kinley
PY - 2025/2/13
Y1 - 2025/2/13
N2 - Tuberculosis (TB) is one of the major public health issues in Bhutan. This study aimed to evaluate epidemiology of TB and predictors of poor treatment outcomes in Sarpang District, Bhutan. A retrospective cohort study was conducted using TB case-based surveillance data of Sarpang District from 2005 to 2021. The outcome of interest was poor treatment outcome. The potential predictors were analyzed using logistic regression. A total of 1704 TB cases were analyzed in this study. The poor outcome in this study was 6.6% with 2.6% deaths due to TB. The patients older than 65 years (adjusted odds ratio [AOR] = 3.58, 95% confidence interval [CI] = [1.45, 7.90]) and sputum non-conversion in the second month with acid-fast bacilli results of scanty (AOR = 3.08, 95% CI = [1.29, 7.34]), 1+ (AOR = 7.12, 95% CI = [3.06, 16.53]), and 2+ (AOR = 21.05, 95% CI = [5.56, 79.63]) were the significant predictors of poor treatment outcome. Therefore, older age and sputum non-conversion in the second month should be given priority.
AB - Tuberculosis (TB) is one of the major public health issues in Bhutan. This study aimed to evaluate epidemiology of TB and predictors of poor treatment outcomes in Sarpang District, Bhutan. A retrospective cohort study was conducted using TB case-based surveillance data of Sarpang District from 2005 to 2021. The outcome of interest was poor treatment outcome. The potential predictors were analyzed using logistic regression. A total of 1704 TB cases were analyzed in this study. The poor outcome in this study was 6.6% with 2.6% deaths due to TB. The patients older than 65 years (adjusted odds ratio [AOR] = 3.58, 95% confidence interval [CI] = [1.45, 7.90]) and sputum non-conversion in the second month with acid-fast bacilli results of scanty (AOR = 3.08, 95% CI = [1.29, 7.34]), 1+ (AOR = 7.12, 95% CI = [3.06, 16.53]), and 2+ (AOR = 21.05, 95% CI = [5.56, 79.63]) were the significant predictors of poor treatment outcome. Therefore, older age and sputum non-conversion in the second month should be given priority.
U2 - 10.1177/10105395251318112
DO - 10.1177/10105395251318112
M3 - Article
C2 - 39945083
SN - 1010-5395
SP - 1
EP - 8
JO - Asia-Pacific Journal of Public Health
JF - Asia-Pacific Journal of Public Health
ER -
