The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes

Alannah K A McKay, David B Pyne, Peter Peeling, Avish P Sharma, Megan L R Ross, Louise M Burke

Research output: Contribution to journalArticle

Abstract

Carbohydrate (CHO) availability could alter mucosal immune responses to exercise. This study compared the effect of three dietary approaches to CHO availability on resting and post-exercise s-IgA levels. Elite race walkers (n = 26) adhered to a high CHO diet (HCHO), periodised CHO availability (PCHO) or a low CHO/high fat diet (LCHF) for 3 weeks while completing an intensified training program. HCHO and PCHO groups consumed 8.0-8.5 g.kg-1 CHO daily, with timing of ingestion manipulated to alter CHO availability around key training sessions. The LCHF diet comprised 80% fat and restricted CHO to < 50 g.day-1. A race walk test protocol (19 km females, 25 km males) was completed at baseline, after adaptation, and following CHO restoration. On each occasion, saliva samples were obtained pre- and post-exercise to quantify s-IgA levels. Resting s-IgA secretion rate substantially increased ~ two-fold post-intervention in all groups (HCHO: 2.2 ± 2.2, PCHO: 2.8 ± 3.2, LCHF: 1.6 ± 1.6; fold-change± 95% confidence limits), however, no substantial differences between dietary treatments were evident. Post-exercise, substantial 20-130% increases in s-IgA concentration and 43-64% reductions in flow rate occurred in all dietary treatments, with trivial differences evident between groups. It appears that high volume training overrides any effect of manipulating CHO availability on mucosal immunity in elite athletes.

LanguageEnglish
Pages553-559
Number of pages7
JournalJournal of Sports Sciences
Volume37
Issue number5
Early online date12 Sep 2018
DOIs
StatePublished - 2019

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Mucosal Immunity
Athletes
Immunoglobulin A
Carbohydrates
Exercise
High Fat Diet
Diet
Walkers
Saliva
Eating
Fats
Education
Therapeutics

Cite this

McKay, A. K. A., Pyne, D. B., Peeling, P., Sharma, A. P., Ross, M. L. R., & Burke, L. M. (2019). The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes. Journal of Sports Sciences, 37(5), 553-559. DOI: 10.1080/02640414.2018.1521712
McKay, Alannah K A ; Pyne, David B ; Peeling, Peter ; Sharma, Avish P ; Ross, Megan L R ; Burke, Louise M. / The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes. In: Journal of Sports Sciences. 2019 ; Vol. 37, No. 5. pp. 553-559
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The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes. / McKay, Alannah K A; Pyne, David B; Peeling, Peter; Sharma, Avish P; Ross, Megan L R; Burke, Louise M.

In: Journal of Sports Sciences, Vol. 37, No. 5, 2019, p. 553-559.

Research output: Contribution to journalArticle

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