Crohn's disease (CD) is thought to result from an inappropriate, ongoing immune response that occurs in genetically susceptible individuals as a result of a complex interaction between luminal bacteria, environmental factors, and the mucosal immune system. Three theories of microbial etiopathogenesis have been proposed:1 (i) a dysbiosis (an imbalance between potentially “beneficial” and potentially “harmful” bacteria); (ii) the presence of an unidentified pathogen; and (iii) excessive bacterial translocation.
|Number of pages||3|
|Journal||Journal of Gastroenterology and Hepatology (Australia)|
|Publication status||Published - May 2013|