Abstract
Crohn's disease (CD) is thought to result from an inappropriate, ongoing immune response that occurs in genetically susceptible individuals as a result of a complex interaction between luminal bacteria, environmental factors, and the mucosal immune system. Three theories of microbial etiopathogenesis have been proposed:1 (i) a dysbiosis (an imbalance between potentially “beneficial” and potentially “harmful” bacteria); (ii) the presence of an unidentified pathogen; and (iii) excessive bacterial translocation.
Original language | English |
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Pages (from-to) | 757-759 |
Number of pages | 3 |
Journal | Journal of Gastroenterology and Hepatology (Australia) |
Volume | 28 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2013 |
Externally published | Yes |