Abstract
Crohn's disease (CD) is thought to result from an inappropriate, ongoing immune response that occurs in genetically susceptible individuals as a result of a complex interaction between luminal bacteria, environmental factors, and the mucosal immune system. Three theories of microbial etiopathogenesis have been proposed:1 (i) a dysbiosis (an imbalance between potentially “beneficial” and potentially “harmful” bacteria); (ii) the presence of an unidentified pathogen; and (iii) excessive bacterial translocation.
| Original language | English |
|---|---|
| Pages (from-to) | 757-759 |
| Number of pages | 3 |
| Journal | Journal of Gastroenterology and Hepatology (Australia) |
| Volume | 28 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2013 |
| Externally published | Yes |