Abstract
There is a growing interest in the use of thiopurines for inflammatory bowel disease. Pharmacogenetic insights suggest that the genetic profile of thiopurine S-methyltransferase and inosine triphosphate pyrophosphatase may affect the clinical response to thiopurines. This is a review on the pharmacogenetics of these enzymes and highlights difficulties that impede prior-to-treat pharmacogenetic testing for the thiopurines in practice.
| Original language | English |
|---|---|
| Pages (from-to) | 213-215 |
| Number of pages | 3 |
| Journal | Journal of Pharmacy Practice and Research |
| Volume | 35 |
| Issue number | 3 |
| Publication status | Published - 1 Sept 2005 |
| Externally published | Yes |