Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds

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    Abstract

    Over the last few years, there has been a dramatic increase in the number of publications in the field of lipase-catalyzed reactions performed in common organic solvents, ionic liquids or even non-conventional solvents. A fairly large percentage of these publications have emerged from organic chemists who have recognized the potential of biocatalysis as a viable and popular technique in organic synthesis. Considerable research has shown that reactions catalyzed by enzymes are more selective and efficiently performed than many of their analogues in the organic chemistry laboratory. This review article focuses on some of the recent developments in the rapidly growing field of lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds. The literature search is dated back to the last five years and covers some comprehensive examples.

    Original languageEnglish
    Pages (from-to)1721-1754
    Number of pages34
    JournalTetrahedron
    Volume63
    Issue number8
    DOIs
    Publication statusPublished - 2007

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