TY - JOUR
T1 - Visual performance of myopia control soft contact lenses in non-presbyopic myopes
AU - Sha, Jennifer
AU - Tilia, Daniel
AU - Diec, Jennie
AU - Fedtke, Cathleen
AU - Yeotikar, Nisha
AU - Jong, Monica
AU - Thomas, Varghese
AU - Bakaraju, Ravi C
N1 - Funding Information:
The authors would like to acknowledge the clinical team (Ms K. Wagenfeuhr, Ms E. Robertson, and Ms B. Ludlow) and the database management team (Dr T. Naduvilath and Ms K. Laarakkers) for their invaluable support to run this trial at the CRTC, Brien Holden Vision Institute, Sydney, NSW, Australia. The authors would also like to acknowledge Dr J. Flanagan for reviewing the manuscript. This project is entirely funded by the Brien Holden Vision Institute. The Brien Holden Vision Institute has proprietary interests in the
Funding Information:
The authors would like to acknowledge the clinical team (Ms K. Wagenfeuhr, Ms E. Robertson, and Ms B. Ludlow) and the database management team (Dr T. Naduvilath and Ms K. Laarakkers) for their invaluable support to run this trial at the CRTC, Brien Holden Vision Institute, Sydney, NSW, Australia. The authors would also like to acknowledge Dr J. Flanagan for reviewing the manuscript. This project is entirely funded by the Brien Holden Vision Institute. The Brien Holden Vision Institute has proprietary interests in the intellectual property governing extended-depth-of-focus contact lenses (Patent application number WO2014059465 A1).
Publisher Copyright:
© 2018 Sha et al.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2018
Y1 - 2018
N2 - Purpose: To compare the visual performance of soft contact lenses reported to reduce myopia progression.Methods: In a double-blind, randomized, crossover trial, 30 non-presbyopic myopes wore MiSight™, center-distance Proclear® Multifocal (+2.00 D add), and two prototype lenses for 1 week each. High- and low-contrast visual acuities at 6 m, and 70 and 40 cm; stereopsis at 40 cm; accommodative facility at 33 cm; and horizontal phoria at 3 m and 33 cm were measured after 1 week. Subjective performance was assessed on a numeric rating scale for vision clarity, lack of ghosting, vision stability, haloes, overall vision satisfaction, and ocular comfort. Frequency of eye-strain symptoms and willingness to purchase lenses were also reported with categorical responses. Participants reported wearing times (total and visually acceptable). Linear mixed models and chi-square tests were employed in analysis with level of significance set at 5%. Theoretical optical performance of all lenses was assessed with schematic myopic model eyes (-1.00, -3.00, and -6.00 D) by comparing the slope of the edge spread function (ESF), an indicator for optical performance/resolution and the blur patch size of the line spread function, an indicator for contrast, between the lenses.Results: Proclear Multifocal and MiSight provided the best distance acuities. However, the prototype lenses were rated significantly higher for many subjective variables, and there were no subjective variables where commercial lenses were rated significantly higher than the prototypes. Theoretical optical performance showed steeper slopes of the ESF and greater blur patch sizes of the LSP with commercial lenses, supporting the clinical findings of better visual acuities but reduced subjective performance. Participants wore prototypes longer and reported their vision acceptable for longer each day compared to MiSight. Both prototypes had the highest willingness-to-purchase rate.Conclusions: The prototypes were better tolerated by myopes compared to the commercial soft contact lenses currently used for slowing myopia progression.
AB - Purpose: To compare the visual performance of soft contact lenses reported to reduce myopia progression.Methods: In a double-blind, randomized, crossover trial, 30 non-presbyopic myopes wore MiSight™, center-distance Proclear® Multifocal (+2.00 D add), and two prototype lenses for 1 week each. High- and low-contrast visual acuities at 6 m, and 70 and 40 cm; stereopsis at 40 cm; accommodative facility at 33 cm; and horizontal phoria at 3 m and 33 cm were measured after 1 week. Subjective performance was assessed on a numeric rating scale for vision clarity, lack of ghosting, vision stability, haloes, overall vision satisfaction, and ocular comfort. Frequency of eye-strain symptoms and willingness to purchase lenses were also reported with categorical responses. Participants reported wearing times (total and visually acceptable). Linear mixed models and chi-square tests were employed in analysis with level of significance set at 5%. Theoretical optical performance of all lenses was assessed with schematic myopic model eyes (-1.00, -3.00, and -6.00 D) by comparing the slope of the edge spread function (ESF), an indicator for optical performance/resolution and the blur patch size of the line spread function, an indicator for contrast, between the lenses.Results: Proclear Multifocal and MiSight provided the best distance acuities. However, the prototype lenses were rated significantly higher for many subjective variables, and there were no subjective variables where commercial lenses were rated significantly higher than the prototypes. Theoretical optical performance showed steeper slopes of the ESF and greater blur patch sizes of the LSP with commercial lenses, supporting the clinical findings of better visual acuities but reduced subjective performance. Participants wore prototypes longer and reported their vision acceptable for longer each day compared to MiSight. Both prototypes had the highest willingness-to-purchase rate.Conclusions: The prototypes were better tolerated by myopes compared to the commercial soft contact lenses currently used for slowing myopia progression.
KW - Accommodation
KW - Extended depth of focus
KW - Theoretical optical performance
U2 - 10.2147/OPTO.S167297
DO - 10.2147/OPTO.S167297
M3 - Article
C2 - 30319298
SN - 1179-2752
VL - 10
SP - 75
EP - 86
JO - Clinical Optometry
JF - Clinical Optometry
ER -