Voxel-wise analysis for spatial characterisation of pseudo-ct errors in MRI-only radiotherapy planning

Hilda Chourak, Anais Barateau, Eugenia Mylona, Capucine Cadin, Caroline Lafond, Peter Greer, Jason Dowling, Jean-Claude-Nunes, Renaud De Crevoisier, Oscar Acosta

Research output: A Conference proceeding or a Chapter in BookConference contributionpeer-review

Abstract

Several approaches have been proposed to generate pseudo computed tomography (pCT) from MR images for radiotherapy dose calculation. Quantification of errors in pCT has been reported using global scores disregarding spatial heterogeneity. The aim of this work was to propose a population voxel-based workflow allowing the local assessment of errors in the generation of pCTs from MRI. For the voxel-wise analysis to be anatomically meaningful, a robust customized inter-patient non-rigid registration method brought the population images to the same coordinate system. To illustrate the use of this methodology, four pCT generation methods were compared: atlas-based, patch-based, and two deep learning methods. Considering global and local scores, deep learning appeared widely superior. Main source of errors were found in the cortical bones. The proposed workflow paves the way for quality control procedures within the clinical workflow.

Original languageEnglish
Title of host publication2021 IEEE 18th International Symposium on Biomedical Imaging, ISBI 2021
Place of PublicationUnited States
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages395-399
Number of pages5
ISBN (Electronic)9781665412469
ISBN (Print)9781665429474
DOIs
Publication statusPublished - 13 Apr 2021
Externally publishedYes
Event18th IEEE International Symposium on Biomedical Imaging, ISBI 2021 - Nice, France
Duration: 13 Apr 202116 Apr 2021

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2021-April
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference18th IEEE International Symposium on Biomedical Imaging, ISBI 2021
Country/TerritoryFrance
CityNice
Period13/04/2116/04/21

Fingerprint

Dive into the research topics of 'Voxel-wise analysis for spatial characterisation of pseudo-ct errors in MRI-only radiotherapy planning'. Together they form a unique fingerprint.

Cite this