Weaned but weary: One third of adult intensive care patients mechanically ventilated for 7 days or more have impaired inspiratory muscle endurance after successful weaning

Bernie BISSETT, Isabel Leditschke, Teresa Neeman, Robert Boots, Jennifer Paratz

Research output: Contribution to journalArticle

12 Citations (Scopus)


Objectives: The purpose of this study was to establish whether intensive care unit (ICU) patients have impaired inspiratory muscle (IM) endurance immediately following weaning from prolonged mechanical ventilation (MV), and whether IM weakness is related to function or perceived exertion. Background: Impaired IM endurance may hinder recovery from MV, however it is unknown whether this affects patients' function or perceived exertion. Methods: Prospective observational study of 43 adult ICU patients following weaning from MV (>7 days duration). IM endurance was measured using the fatigue resistance index (FRI). Results: IM endurance was impaired (FRI=mean 0.90, SD 0.31), with 37% scoring below 0.80. IM strength did not significantly correlate with function (. r=0.24, p=0.12) or perceived exertion during exercise (. r=-0.146, p=0.37). Conclusions: IM endurance is reduced in one third of patients, while IM weakness does not appear closely associated with function or perceived exertion immediately following successful weaning.
Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalHeart and Lung
Issue number1
Publication statusPublished - 1 Jan 2015


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