Isolation and characterisation of proteins from Streptococcus pneumoniae for determination of vaccine potential

  • Maha Jomaa

    Student thesis: Doctoral Thesis


    The purpose of this study was to investigate novel pneumococcal proteins for potential
    to induce an immune response that cleared an acute pulmonary infection in a mouse
    model. Proteins were purified from the cell wall of S. pneumoniae and screened in an
    animal model of acute lung infection following mucosa! immunisations. Three proteins
    were identified as showing potential as new vaccine candidates and investigations
    associated with these proteins are presented in this thesis.
    Date of Award2004
    Original languageEnglish
    SupervisorJennelle Kyd (Supervisor) & Allan W. Cripps (Supervisor)

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